Allisartan Isoproxil/Amlodipine Besylate

To evaluate the efficacy and safety of olisartan medoxomil and amlodipine tablets in patients with essential hypertension whose blood pressure cannot be effectively controlled after 4 weeks of monotherapy.

Under fasting conditions, healthy adult subjects were given a single oral dose of allisartan medoxomil amlodipine tablets (240 mg/5 mg) and allisartan medoxomil (240 mg) combined with amlodipine besylate tablets (5 mg) to evaluate the bioequivalence of allisartan medoxomil amlodipine tablets and allisartan medoxomil tablets combined with amlodipine besylate tablets, and to observe the safety of allisartan medoxomil amlodipine tablets and allisartan medoxomil tablets combined with amlodipine besylate tablets in healthy subjects.