Allisartan Isoproxil/Amlodipine Besylate

Under fasting conditions, healthy adult subjects were given a single oral dose of allisartan medoxomil amlodipine tablets (240 mg/5 mg) and allisartan medoxomil (240 mg) combined with amlodipine besylate tablets (5 mg) to evaluate the bioequivalence of allisartan medoxomil amlodipine tablets and allisartan medoxomil tablets combined with amlodipine besylate tablets, and to observe the safety of allisartan medoxomil amlodipine tablets and allisartan medoxomil tablets combined with amlodipine besylate tablets in healthy subjects.

Primary objective To evaluate the bioequivalence of single-dose of olisartan medoxomil amlodipine tablets (240mg/5mg) and Fulitan (alisartan medoxomil amlodipine tablets, 240mg/5mg) in healthy adult subjects after a single oral administration under fasting conditions. Secondary objective To observe the safety of single-dose of olisartan medoxomil amlodipine tablets (240mg/5mg) and Fulitan® (alisartan medoxomil amlodipine tablets, 240mg/5mg) in healthy subjects.