Last update 21 Nov 2024

YKST02

Overview

Basic Info

Drug Type
Bispecific T-cell Engager (BiTE)
Synonyms
Target
BCMA x CD3
Mechanism
BCMA inhibitors(B-cell maturation protein inhibitors), CD3 stimulants(T cell surface glycoprotein CD3 stimulants)
Therapeutic Areas
NeoplasmsImmune System DiseasesCardiovascular Diseases+ [2]
Active Indication
Plasma cell myeloma refractoryGlomerulonephritis, IGA
Inactive Indication-
Originator Organization
Excyte Biopharma LtdExcyte Biopharma Ltd
Active Organization
Excyte Biopharma LtdExcyte Biopharma Ltd
Inactive Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with YKST02
NCT06574568 / RecruitingPhase 1
A Multicenter, Open-label, Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Antitumor Efficacy of YKST02 in Participants with Relapsed or Refractory Multiple Myeloma
CTR20241570 / RecruitingPhase 1
评价YKST02治疗复发/难治性多发性骨髓瘤的安全性、耐受性、药代动力学特征和初步抗肿瘤疗效的多中心、开放性、I期临床研究
[Translation] A multicenter, open-label, phase I clinical study to evaluate the safety, tolerability, pharmacokinetic characteristics and preliminary anti-tumor efficacy of YKST02 in the treatment of relapsed/refractory multiple myeloma
100 Clinical Results associated with YKST02
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100 Translational Medicine associated with YKST02
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100 Patents (Medical) associated with YKST02
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100 Deals associated with YKST02
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Plasma cell myeloma refractoryPhase 1
CN
Excyte Biopharma LtdExcyte Biopharma Ltd
14 Jun 2024
Glomerulonephritis, IGAPreclinical
CN
Excyte Biopharma LtdExcyte Biopharma Ltd
01 Oct 2024
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Clinical Result

Indication
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Approval

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Regulation

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