Last update 27 Feb 2026

SCH-900978

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
SCH 900978
Target
Neuropeptide receptor
Action
antagonists
Mechanism
Neuropeptide receptor antagonists
Therapeutic Areas
Other DiseasesNervous System DiseasesRespiratory Diseases+ [1]
Active Indication-
Inactive Indication
Chemotherapy-induced nausea and vomitingCoughDepressive Disorder, Major+ [3]
Originator Organization
Merck Sharp & Dohme Corp.Merck Sharp & Dohme Corp.
Active Organization-
Inactive Organization
OPKO Health, Inc.OPKO Health, Inc.Merck Sharp & Dohme Corp.Merck Sharp & Dohme Corp.
License Organization-
Drug Highest PhaseDiscontinuedPhase 2
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC25H23F6N5O2
InChIKeyACZWFJDLNLZWDP-ZGNKEGEESA-N
CAS Registry873947-10-5

Related

100 Clinical Results associated with SCH-900978
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100 Translational Medicine associated with SCH-900978
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100 Patents (Medical) associated with SCH-900978
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100 Deals associated with SCH-900978
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Chemotherapy-induced nausea and vomitingPhase 2
United States
OPKO Health, Inc.OPKO Health, Inc.
-
NauseaPhase 2-
Merck Sharp & Dohme Corp.Merck Sharp & Dohme Corp.
-
NauseaPhase 2-
OPKO Health, Inc.OPKO Health, Inc.
-
VomitingPhase 2-
OPKO Health, Inc.OPKO Health, Inc.
-
VomitingPhase 2-
Merck Sharp & Dohme Corp.Merck Sharp & Dohme Corp.
-
CoughPhase 1
United States
OPKO Health, Inc.OPKO Health, Inc.
-
Depressive Disorder, MajorPhase 1
United States
OPKO Health, Inc.OPKO Health, Inc.
-
Urinary Bladder, OveractivePhase 1
United States
OPKO Health, Inc.OPKO Health, Inc.
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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