Last update 30 Jan 2026

Cam161533

Overview

Basic Info

Drug Type
Trispecific killer cell engager (TriKE)
Synonyms-
Target
CD16 x CD33 x IL-15
Action
activators, inhibitors, agonists
Mechanism
CD16 activators(FcγRIII activators), CD33 inhibitors(Myeloid cell surface antigen CD33 inhibitors), IL-15 agonists(Interleukin-15 agonists)
Therapeutic Areas
NeoplasmsHemic and Lymphatic Diseases
Active Indication
Acute Myeloid Leukemia
Inactive Indication-
Originator Organization
Nektar TherapeuticsNektar TherapeuticsNationwide Children's HospitalNationwide Children's HospitalNew York Medical CollegeNew York Medical College
Active Organization
Nektar TherapeuticsNektar TherapeuticsNew York Medical CollegeNew York Medical CollegeNationwide Children's HospitalNationwide Children's Hospital
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with Cam161533
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100 Translational Medicine associated with Cam161533
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100 Patents (Medical) associated with Cam161533
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100 Deals associated with Cam161533
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute Myeloid LeukemiaPreclinical
United States
Nektar TherapeuticsNektar Therapeutics
05 Nov 2025
Acute Myeloid LeukemiaPreclinical
United States
New York Medical CollegeNew York Medical College
05 Nov 2025
Acute Myeloid LeukemiaPreclinical
United States
Nationwide Children's HospitalNationwide Children's Hospital
05 Nov 2025
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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