Last update 26 Jul 2025

dMCL1-6

Overview

Basic Info

Drug Type
Proteolysis-targeting chimeras (PROTAC)
Synonyms
dMCL1-6
Target
Mcl-1
Action
degraders
Mechanism
Mcl-1 degraders(Induced myeloid leukemia cell differentiation protein Mcl-1 degraders)
Therapeutic Areas
Neoplasms
Active Indication-
Inactive Indication
Neoplasms
Originator Organization
University of CalgaryUniversity of Calgary
Active Organization-
Inactive Organization
University of CalgaryUniversity of Calgary
License Organization-
Drug Highest PhasePendingPreclinical
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC63H67N9O12
InChIKeyJZQOTODZTIWWFI-UHFFFAOYSA-N
CAS Registry-

Related

100 Clinical Results associated with dMCL1-6
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100 Translational Medicine associated with dMCL1-6
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100 Patents (Medical) associated with dMCL1-6
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100 Deals associated with dMCL1-6
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
NeoplasmsPreclinical
Canada
University of CalgaryUniversity of Calgary
22 May 2019
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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