Delving into the Latest Updates on GST HG 151 with Synapse

Overview

Basic Info

Drug Type

Small molecule drug

Synonyms

Target

Mechanism

ASK1 inhibitors(Apoptosis signal-regulating kinase 1 inhibitors), JNK inhibitors(c-Jun N-terminal kinase inhibitors), p38 MAPK stimulants(P38 mitogen-activated protein kinase stimulants)

Therapeutic Areas

Digestive System Disorders

Active Indication

Nonalcoholic Steatohepatitis

Inactive Indication-

Originator Organization

Fujian Cosunter Pharmaceutical Co., Ltd.

Active Organization

Fujian Cosunter Pharmaceutical Co., Ltd.

Inactive Organization-

Drug Highest PhasePhase 1

First Approval Date-

Regulation-

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评估健康成人空腹条件下单次和多次口服GST-HG151的安全性和耐受性；评估健康成人空腹条件下单次和多次口服GST-HG151的药代动力学特征；评估食物对健康成人单次口服GST-HG151药代动力学的影响初步探索GST-HG151片的药物代谢转化。

[Translation]

To evaluate the safety and tolerability of single and multiple oral administrations of GST-HG151 in healthy adults under fasting conditions; To evaluate the pharmacokinetic characteristics of single and multiple oral administrations of GST-HG151 in healthy adults under fasting conditions; To evaluate the effect of food on the pharmacokinetics of single oral administration of GST-HG151 in healthy adults To preliminarily explore the drug metabolism transformation of GST-HG151 tablets.

Start Date07 Mar 2022

Sponsor / Collaborator

Fujian Cosunter Pharmaceutical Co., Ltd.