Delving into the Latest Updates on Lactomin(ISEI Co., Inc.) with Synapse

Overview

Basic Info

Drug Type

Probiotics

Synonyms

Lactomin (Isei Pharm)

Target-

Action

modulators

Mechanism

Bacteria replacements, Microbiome modulators

Therapeutic Areas

Digestive System Disorders

Active Indication

Digestive System Disorders

Inactive Indication-

Originator Organization

ISEI Co., Inc.

Active Organization

ISEI Co., Inc.

Inactive Organization-

License Organization-

Drug Highest PhaseApproved

First Approval Date

Japan (01 Jan 2009),

Digestive System Disorders

Regulation-

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cf. C.A. 49, 12777i.Tablets were compressed during a short period, their weight variation was estimated as coefficient of variance, and the effects were studied of (1) the nature of the tablet base, (2) the size of particles to be compressed (or granulated sieve mesh), (3) the diameter of tablet, and (4) the speed of compression.The tablet bases used were (1) 50% CaCO₃, 40% lactose, and 10% potato starch, (2) 100% lactose, and (3) 90% lactomin and 10% potato starch; the sieves tested were of 12, 14, 16, 18, and 20 mesh; diameters of 7, 10, and 13 mm.; and speeds of 76 and 42 tablets/min.Results showed no significant difference among the 3 tablet bases, or between the 2 speeds of compression.Decrease of diameter and of sieve mesh increased the weight variation of the tablets quadratically and linearly, resp.The recommended conditions for compression of tablets were sieves of 19, 16, and 15 mesh (or below) for 7, 10, and 13 diameters, resp.

100 Deals associated with Lactomin(ISEI Co., Inc.)

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