Last update 08 May 2025

NZP-196

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Target
TGR5
Action
agonists
Mechanism
TGR5 agonists(G-protein coupled bile acid receptor 1 agonists)
Therapeutic Areas
Nervous System DiseasesDigestive System DisordersEndocrinology and Metabolic Disease+ [1]
Active Indication
InflammationLiver DiseasesMetabolic Diseases+ [1]
Inactive Indication-
Originator Organization
New Zealand Pharmaceuticals Ltd.New Zealand Pharmaceuticals Ltd.
Active Organization
New Zealand Pharmaceuticals Ltd.New Zealand Pharmaceuticals Ltd.
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC28H49NNaO6S
InChIKeyUIXKWNINXABQFM-UKWCPTHLSA-N
CAS Registry3027426-02-1

Related

100 Clinical Results associated with NZP-196
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100 Translational Medicine associated with NZP-196
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100 Patents (Medical) associated with NZP-196
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1
Literatures (Medical) associated with NZP-196
01 Mar 2023European Journal of Medicinal Chemistry
The discovery of 12β-methyl-17-epi-18-nor-bile acids as potent and selective TGR5 agonists
100 Deals associated with NZP-196
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
InflammationPreclinical
New Zealand
New Zealand Pharmaceuticals Ltd.New Zealand Pharmaceuticals Ltd.
25 Jan 2023
Liver DiseasesPreclinical
New Zealand
New Zealand Pharmaceuticals Ltd.New Zealand Pharmaceuticals Ltd.
25 Jan 2023
Metabolic DiseasesPreclinical
New Zealand
New Zealand Pharmaceuticals Ltd.New Zealand Pharmaceuticals Ltd.
25 Jan 2023
Neurodegenerative DiseasesPreclinical
New Zealand
New Zealand Pharmaceuticals Ltd.New Zealand Pharmaceuticals Ltd.
25 Jan 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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