Last update 18 Oct 2025

CHT-102

Overview

Basic Info

Drug Type
CAR-T
Synonyms
CHT102 allogeneic CAR T cells(Tianjin Medical University Cancer Institute and Hospital), CHT-102
Target
MSLN
Action
inhibitors
Mechanism
MSLN inhibitors(Mesothelin inhibitors)
Therapeutic Areas
NeoplasmsDigestive System DisordersEndocrinology and Metabolic Disease
Active Indication
Pancreatic CancerAdvanced Malignant Solid NeoplasmMesothelin positive Solid Tumors+ [1]
Inactive Indication-
Originator Organization
Tianjin Medical University Cancer Institute and HospitalTianjin Medical University Cancer Institute and Hospital
Active Organization
Nanjing Calmhome Cell & Gene Engineering Institute Co., Ltd.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with CHT-102
NCT06760364
/ RecruitingPhase 1IIT
A Single-Arm, Open-Label, Phase I Study of CHT102 for MSLN-Positive Advanced Pancreatic Cancer
NCT06717022
/ RecruitingNot ApplicableIIT
A Clinical Study of CHT102, a Universal Chimeric Antigen Receptor T-Cell Immunotherapy(U CAR-T) for Mesothelin(MSLN) Positive Advanced Solid Tumors: a Single-arm, Open-label, Dose Escalation and Expansion Clinical Study
100 Clinical Results associated with CHT-102
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100 Translational Medicine associated with CHT-102
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100 Patents (Medical) associated with CHT-102
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100 Deals associated with CHT-102
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Pancreatic CancerPhase 1
China
Nanjing Calmhome Cell & Gene Engineering Institute Co., Ltd.
25 Dec 2024
Advanced Malignant Solid NeoplasmClinical
China
Nanjing Calmhome Cell & Gene Engineering Institute Co., Ltd.
06 May 2024
Mesothelin positive Solid TumorsClinical
China
Nanjing Calmhome Cell & Gene Engineering Institute Co., Ltd.
06 May 2024
Metastatic Solid TumorClinical
China
Nanjing Calmhome Cell & Gene Engineering Institute Co., Ltd.
06 May 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Clinical Trial

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Approval

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Regulation

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