Last update 05 Jul 2025

HOT-1030

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
HOT 1030, HOT1030
Target
4-1BB
Action
agonists
Mechanism
4-1BB agonists(Tumor necrosis factor receptor superfamily member 9 agonists)
Therapeutic Areas
Neoplasms
Active Indication
Advanced Malignant Solid Neoplasm
Inactive Indication-
Originator Organization-
Active Organization
Shanghai Huaaotai Biopharmaceutical Co., Ltd.Shanghai Huaaotai Biopharmaceutical Co., Ltd.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with HOT-1030
CTR20202606
/ RecruitingPhase 1
HOT-1030注射液治疗晚期恶性实体肿瘤单中心、开放、剂量递增的Ia期临床研究
[Translation] A single-center, open-label, dose-escalation phase Ia clinical study of HOT-1030 injection in the treatment of advanced malignant solid tumors
NCT05060263
/ Unknown statusPhase 1
A Phase 1, Open-label, Dose-escalation Study of the Safety and Pharmacokinetics of HOT1030 in Patients With Advanced Solid Tumors
100 Clinical Results associated with HOT-1030
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100 Translational Medicine associated with HOT-1030
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100 Patents (Medical) associated with HOT-1030
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100 Deals associated with HOT-1030
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 1
China
Shanghai Huaaotai Biopharmaceutical Co., Ltd.Shanghai Huaaotai Biopharmaceutical Co., Ltd.
15 Mar 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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