Last update 01 Nov 2024

HG-205

Overview

Basic Info

Drug Type
CRISPR/Cas
Synonyms
CRISPR/Cas13X RNA base-editing gene therapy (Cholgene), HG 205, HG205
Target
OTOF Q829X
Mechanism
OTOF Q829X modulators
Therapeutic Areas
Nervous System DiseasesOtorhinolaryngologic Diseases
Active Indication
Hearing Loss
Inactive Indication-
Originator Organization
HuidaGene Therapeutics Co., Ltd.HuidaGene Therapeutics Co., Ltd.Startup
Active Organization
HuidaGene Therapeutics Co., Ltd.HuidaGene Therapeutics Co., Ltd.Startup
Inactive Organization-
Drug Highest PhaseEarly Phase 1
First Approval Date-
RegulationOrphan Drug (US), Rare Pediatric Disease (US)
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Related

1
Clinical Trials associated with HG-205
NCT06025032 / Not yet recruitingEarly Phase 1
An Open-label, Multiple-cohort, Dose-finding, Investigator-initiated Trial to Evaluate the Safety, Tolerability, and Efficacy of HG205 RNA Base-Editing Therapy in Subjects With OTOF-p.Q829X Mutation-associated Hearing Loss
100 Clinical Results associated with HG-205
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100 Translational Medicine associated with HG-205
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100 Patents (Medical) associated with HG-205
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100 Deals associated with HG-205
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hearing LossPhase 1
CN
HuidaGene Therapeutics Co., Ltd.HuidaGene Therapeutics Co., Ltd.Startup
06 Sep 2023
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Clinical Result

Indication
Phase
Evaluation
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Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Approval

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Regulation

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