Last update 20 Jun 2024

Buprenorphine Hydrochloride/Granisetron

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Buprenorphine/granisetron, BB-0417, BB0417
+ [2]
Target
5-HT3 receptor x κ opioid receptor x μ opioid receptor
Mechanism
5-HT3 receptor antagonists(Serotonin 3 (5-HT3) receptor antagonists), κ opioid receptor antagonists(Kappa opioid receptor antagonists), μ opioid receptor agonists(Mu opioid receptor agonists)
Therapeutic Areas
Nervous System DiseasesOther Diseases
Active Indication-
Inactive Indication
Pain, PostoperativePostoperative Nausea and Vomiting
Originator Organization
Camurus ABCamurus AB
Active Organization-
Inactive Organization
Braeburn, Inc.Braeburn, Inc.Camurus ABCamurus AB
Drug Highest PhasePendingPhase 1
First Approval Date-
Regulation-

Structure

Molecular FormulaC18H24N4O
InChIKeyMFWNKCLOYSRHCJ-BTTYYORXSA-N
CAS Registry109889-09-0
View All Structures (2)

Related

100 Clinical Results associated with Buprenorphine Hydrochloride/Granisetron
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100 Translational Medicine associated with Buprenorphine Hydrochloride/Granisetron
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100 Patents (Medical) associated with Buprenorphine Hydrochloride/Granisetron
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100 Deals associated with Buprenorphine Hydrochloride/Granisetron
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Pain, PostoperativePhase 1
SE
Camurus AB
-
Pain, PostoperativePhase 1-
Braeburn, Inc.
-
Postoperative Nausea and VomitingPhase 1
SE
Camurus AB
-
Postoperative Nausea and VomitingPhase 1-
Braeburn, Inc.
-
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Clinical Result

Indication
Phase
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Study
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Approval

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Regulation

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