Last update 20 Mar 2025

Buprenorphine Hydrochloride/Granisetron

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Buprenorphine/granisetron
+ [2]
Target
5-HT3 receptor x κ opioid receptor x μ opioid receptor
Action
antagonists, agonists
Mechanism
5-HT3 receptor antagonists(Serotonin 3 (5-HT3) receptor antagonists), κ opioid receptor antagonists(Kappa opioid receptor antagonists), μ opioid receptor agonists(Mu opioid receptor agonists)
Therapeutic Areas
Nervous System DiseasesOther Diseases
Active Indication-
Inactive Indication
Pain, PostoperativePostoperative Nausea and Vomiting
Originator Organization
Camurus ABCamurus AB
Active Organization-
Inactive Organization
Braeburn, Inc.Braeburn, Inc.Camurus ABCamurus AB
Drug Highest PhasePendingPhase 1
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC18H24N4O
InChIKeyMFWNKCLOYSRHCJ-BTTYYORXSA-N
CAS Registry109889-09-0
View All Structures (2)

Related

100 Clinical Results associated with Buprenorphine Hydrochloride/Granisetron
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100 Translational Medicine associated with Buprenorphine Hydrochloride/Granisetron
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100 Patents (Medical) associated with Buprenorphine Hydrochloride/Granisetron
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100 Deals associated with Buprenorphine Hydrochloride/Granisetron
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Pain, PostoperativePhase 1
Sweden
Camurus ABCamurus AB
-
Pain, PostoperativePhase 1-
Braeburn, Inc.Braeburn, Inc.
-
Postoperative Nausea and VomitingPhase 1
Sweden
Camurus ABCamurus AB
-
Postoperative Nausea and VomitingPhase 1-
Braeburn, Inc.Braeburn, Inc.
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Approval

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Regulation

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