Last update 27 Nov 2025

KrasG12D siRNA-loaded mesenchymal stromal cells-derived exosomes (Codiak BioSciences)

Overview

Basic Info

Drug Type
Exosomes, siRNA
Synonyms
iExosomes, Mesenchymal Stromal Cells-derived Exosomes with KRAS G12D siRNA(Codiak BioSciences), MSC-derived Exosomes with KrasG12D siRNA(Codiak BioSciences)
Target
KRAS G12D
Action
inhibitors
Mechanism
KRAS G12D inhibitors(GTPase KRas G12D inhibitors)
Therapeutic Areas
NeoplasmsDigestive System DisordersEndocrinology and Metabolic Disease
Active Indication
Metastatic Pancreatic CancerMetastatic Pancreatic Ductal AdenocarcinomaPancreatic adenocarcinoma metastatic
Inactive Indication-
Originator Organization
MD Anderson Cancer Center Orlando
Active Organization
The University of Texas MD Anderson Cancer CenterThe University of Texas MD Anderson Cancer Center
Inactive Organization
Codiak BioSciences, Inc.Codiak BioSciences, Inc.
License Organization-
Drug Highest PhasePhase 1/2
First Approval Date-
Regulation-
Login to view timeline

Structure/Sequence

Boost your research with our RNA technology data.
login
or
view full example data
Boost your research with our RNA technology data.

Related

1
Clinical Trials associated with KrasG12D siRNA-loaded mesenchymal stromal cells-derived exosomes (Codiak BioSciences)
NCT03608631
/ RecruitingPhase 1/2IIT
Phase I Study of Mesenchymal Stromal Cells-Derived Exosomes With KrasG12D siRNA for Metastatic Pancreas Cancer Patients Harboring KrasG12D Mutation
100 Clinical Results associated with KrasG12D siRNA-loaded mesenchymal stromal cells-derived exosomes (Codiak BioSciences)
Login to view more data
100 Translational Medicine associated with KrasG12D siRNA-loaded mesenchymal stromal cells-derived exosomes (Codiak BioSciences)
Login to view more data
100 Patents (Medical) associated with KrasG12D siRNA-loaded mesenchymal stromal cells-derived exosomes (Codiak BioSciences)
Login to view more data
100 Deals associated with KrasG12D siRNA-loaded mesenchymal stromal cells-derived exosomes (Codiak BioSciences)
Login to view more data

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Metastatic Pancreatic CancerPhase 2
United States
The University of Texas MD Anderson Cancer CenterThe University of Texas MD Anderson Cancer Center
27 Jan 2021
Metastatic Pancreatic Ductal AdenocarcinomaPhase 2
United States
The University of Texas MD Anderson Cancer CenterThe University of Texas MD Anderson Cancer Center
27 Jan 2021
Pancreatic adenocarcinoma metastaticPhase 2
United States
The University of Texas MD Anderson Cancer CenterThe University of Texas MD Anderson Cancer Center
27 Jan 2021
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
login
or
view full example data
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
login
or
view full example data
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
login
or
view full example data
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
login
or
view full example data
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
login
or
view full example data
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
login
or
view full example data
Understand key drug designations in just a few clicks with Synapse.
AI Agents Built for Biopharma Breakthroughs
Accelerate discovery. Empower decisions. Transform outcomes.
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free