Last update 07 Jun 2025

Amlodipine Besylate/Chlorthalidone/Losartan Potassium

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Amoprel, 아모프렐정
Target
AT1R x L-type calcium channel x NCC
Action
antagonists, blockers, inhibitors
Mechanism
AT1R antagonists(Angiotensin II Receptor Type 1 antagonists), L-type calcium channel blockers(Voltage-gated L-type calcium channel blockers), NCC inhibitors(Thiazide-sensitive sodium-chloride cotransporter inhibitors)
Therapeutic Areas
Cardiovascular Diseases
Active Indication
Essential Hypertension
Inactive Indication-
Originator Organization
Hanmi Pharmaceutical Co., Ltd.Hanmi Pharmaceutical Co., Ltd.
Active Organization
Hanmi Pharmaceutical Co., Ltd.Hanmi Pharmaceutical Co., Ltd.
Inactive Organization-
License Organization-
Drug Highest PhaseApproved
First Approval Date
South Korea (30 May 2025),
Essential Hypertension
Regulation-
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Structure/Sequence

Molecular FormulaC22H23ClKN6O
InChIKeyFDKIDFYIEWFERB-UHFFFAOYSA-N
CAS Registry124750-99-8
View All Structures (5)

Related

100 Clinical Results associated with Amlodipine Besylate/Chlorthalidone/Losartan Potassium
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100 Translational Medicine associated with Amlodipine Besylate/Chlorthalidone/Losartan Potassium
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100 Patents (Medical) associated with Amlodipine Besylate/Chlorthalidone/Losartan Potassium
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100 Deals associated with Amlodipine Besylate/Chlorthalidone/Losartan Potassium
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R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Essential Hypertension
South Korea
Hanmi Pharmaceutical Co., Ltd.Hanmi Pharmaceutical Co., Ltd.
30 May 2025
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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