Last update 31 Jul 2026

ZL-65

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
ZL-65
Target
NLRP3
Action
inhibitors
Mechanism
NLRP3 inhibitors(NACHT, LRR and PYD domains-containing protein 3 inhibitors)
Therapeutic Areas
Immune System DiseasesNervous System DiseasesCongenital Disorders+ [3]
Active Indication
Cryopyrin-Associated Periodic SyndromesAmyotrophic Lateral SclerosisParkinson Disease+ [1]
Inactive Indication
Autoinflammatory diseaseGoutMetabolic Dysfunction Associated Steatohepatitis
Originator Organization
Chengdu Zenitar Biomedical Technology Co., LtdChengdu Zenitar Biomedical Technology Co., Ltd
Active Organization
Chengdu Zenitar Biomedical Technology Co., LtdChengdu Zenitar Biomedical Technology Co., Ltd
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
Login to view timeline

Related

1
Clinical Trials associated with ZL-65
CTR20262674
/ Not yet recruitingPhase 1
ZL-65片在中国健康成年试验参与者中的随机双盲、安慰剂对照、单/多次口服给药的剂量递增的安全耐受性、药代动力学和初步药效动力学、食物影响的I期临床研究
[Translation] A randomized, double-blind, placebo-controlled, dose-escalation safety, tolerability, pharmacokinetics, preliminary pharmacodynamics, and food effects phase I clinical study of ZL-65 tablets in healthy adult participants in China.
100 Clinical Results associated with ZL-65
Login to view more data
100 Translational Medicine associated with ZL-65
Login to view more data
100 Patents (Medical) associated with ZL-65
Login to view more data
100 Deals associated with ZL-65
Login to view more data

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Cryopyrin-Associated Periodic SyndromesIND Approval
China
Chengdu Zenitar Biomedical Technology Co., LtdChengdu Zenitar Biomedical Technology Co., Ltd
15 Jan 2026
Amyotrophic Lateral SclerosisPreclinical
China
Chengdu Zenitar Biomedical Technology Co., LtdChengdu Zenitar Biomedical Technology Co., Ltd
01 Jul 2025
Parkinson DiseasePreclinical
China
Chengdu Zenitar Biomedical Technology Co., LtdChengdu Zenitar Biomedical Technology Co., Ltd
01 Jul 2025
Multiple SclerosisPreclinical
China
Chengdu Zenitar Biomedical Technology Co., LtdChengdu Zenitar Biomedical Technology Co., Ltd
22 Aug 2024
Autoinflammatory diseasePreclinical
China
Chengdu Zenitar Biomedical Technology Co., LtdChengdu Zenitar Biomedical Technology Co., Ltd
22 Mar 2024
GoutPreclinical
China
Chengdu Zenitar Biomedical Technology Co., LtdChengdu Zenitar Biomedical Technology Co., Ltd
12 Oct 2022
Metabolic Dysfunction Associated SteatohepatitisPreclinical
China
Chengdu Zenitar Biomedical Technology Co., LtdChengdu Zenitar Biomedical Technology Co., Ltd
12 Oct 2022
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
login
or
view full example data
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
login
or
view full example data
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
login
or
view full example data
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
login
or
view full example data
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
login
or
view full example data
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
login
or
view full example data
Understand key drug designations in just a few clicks with Synapse.
Hiro LS Researcher
The AI Search Engine Built to Accelerate Biopharma Decisions
Search across billion-scale life sciences data to uncover signals, validate evidence, and act with confidence.
Ask any biopharma research question→
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, Patsnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Discover Synapse Data Servers
Synapse data is now integrated into the PatSnap LS Model Context Protocol (MCP) service. Customize your LLM agent now using our MCP server!
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free