Last update 01 Nov 2024

LOXO-260

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
+ [1]
Target
RET
Mechanism
RET inhibitors(Tyrosine-protein kinase receptor RET inhibitors)
Therapeutic Areas
NeoplasmsEndocrinology and Metabolic DiseaseRespiratory Diseases+ [1]
Active Indication
Non-Small Cell Lung CancerRET fusion-positive Solid TumorsThyroid Cancer, Medullary
Inactive Indication-
Originator Organization
Eli Lilly & Co.Eli Lilly & Co.
Active Organization
Eli Lilly & Co.Eli Lilly & Co.
Inactive Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with LOXO-260
NCT05225259 / No longer availableNot Applicable
Expanded Access of LOXO-260 in Participants With RET Mutant or RET Fusion Tumors Refractory to Prior RET Selective TKI Treatment
NCT05241834 / Active, not recruitingPhase 1
A Phase 1 Study of Oral LOXO-260 in Patients With RET Fusion-Positive Solid Tumors, Medullary Thyroid Cancer, and Other Tumors With RET Activation Refractory to Selective RET Inhibitors
100 Clinical Results associated with LOXO-260
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100 Translational Medicine associated with LOXO-260
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100 Patents (Medical) associated with LOXO-260
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100 Deals associated with LOXO-260
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Non-Small Cell Lung CancerPhase 1
US
Eli Lilly & Co.Eli Lilly & Co.
23 Mar 2022
RET fusion-positive Solid TumorsPhase 1
US
Eli Lilly & Co.Eli Lilly & Co.
23 Mar 2022
Thyroid Cancer, MedullaryPhase 1
US
Eli Lilly & Co.Eli Lilly & Co.
23 Mar 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Clinical Trial

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Approval

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Regulation

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