Last update 29 Nov 2025

SEP-225432

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
SEP 228432, SEP-228432
Target
DAT x NET x SERT
Action
inhibitors
Mechanism
Dopamine reuptake inhibitors, NET inhibitors(Norepinephrine transporter inhibitors), Serotonin reuptake inhibitors
Therapeutic Areas-
Active Indication-
Inactive Indication-
Originator Organization
Sumitomo Pharma America, Inc.Sumitomo Pharma America, Inc.
Active Organization-
Inactive Organization
Sumitomo Pharma America, Inc.Sumitomo Pharma America, Inc.
License Organization-
Drug Highest PhasePendingPhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with SEP-225432
NCT01531972
/ CompletedPhase 1
A Phase 1, Open-Label, Single-photon Emission Computed Tomography (SPECT) Study to Evaluate Serotonin and Dopamine Transporter Occupancy After Multiple Dose Administration of SEP-228432 to Achieve Steady State in Healthy Subjects
100 Clinical Results associated with SEP-225432
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100 Translational Medicine associated with SEP-225432
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100 Patents (Medical) associated with SEP-225432
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100 Deals associated with SEP-225432
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R&D Status

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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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