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Last update 29 Nov 2025
HRS-2189
Last update 29 Nov 2025
Overview
Basic Info
Drug Type Small molecule drug |
Synonyms HRS 2189, HRS-2189, HRS2189 |
Target |
Action inhibitors |
Mechanism KAT6A inhibitors(lysine acetyltransferase 6A inhibitors), KAT6B inhibitors(lysine acetyltransferase 6B inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhasePhase 2 |
First Approval Date- |
Regulation- |
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Related
5
Clinical Trials associated with HRS-2189NCT07061210
An Explorative Study of HRS-2189 Combined With Adebrelimab and BP102 for Metastatic Colorectal Cancer
CTR20244182
HRS-2189联合氟维司群±HRS-6209、或联合HRS-8080±HRS-6209、或联合HRS-6209+HRS-1358在晚期不可切除或转移性乳腺癌患者中的安全性、耐受性、药代动力学及初步疗效的开放、多中心的Ib/II期临床研究
[Translation] An open, multicenter, phase Ib/II clinical study of the safety, tolerability, pharmacokinetics, and preliminary efficacy of HRS-2189 combined with fulvestrant ± HRS-6209, or combined with HRS-8080 ± HRS-6209, or combined with HRS-6209 + HRS-1358 in patients with advanced unresectable or metastatic breast cancer
NCT06679036
An Open, Multicenter Phase Ib/II Clinical Study on the Safety, Tolerance, Pharmacokinetics, and Initial Efficacy of HRS-2189 in Combination With Fluvastatin±HRS-6209, or HRS-8080±HRS-6209, or HRS-6209+HRS-1358 in Patients With Advanced Unresectable or Metastatic Breast Cancer
100 Clinical Results associated with HRS-2189
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100 Translational Medicine associated with HRS-2189
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100 Patents (Medical) associated with HRS-2189
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100 Deals associated with HRS-2189
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Metastatic Colorectal Carcinoma | Phase 2 | - | 01 Jul 2025 | |
| Breast Cancer | Phase 2 | China | 21 Jan 2025 | |
| Metastatic Prostate Carcinoma | Phase 2 | China | 31 Dec 2024 | |
| Advanced cancer | Phase 1 | China | 26 May 2023 | |
| Locally Advanced Malignant Solid Neoplasm | Phase 1 | China | 26 May 2023 |
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