[Translation] A randomized, open-label, single-dose and multiple-dose phase II clinical trial of HRG2010 versus carbendazim and levodopa sustained-release tablets in the treatment of Parkinson's disease with symptom fluctuations: pharmacokinetic, pharmacodynamic, efficacy and safety
第一阶段主要目的:在帕金森病伴症状波动患者中比较HRG2010和卡左双多巴缓释片单次给药后的药代动力学(PK)特征;
第二阶段主要目的:评价HRG2010对比卡左双多巴缓释片治疗帕金森病伴症状波动的有效性。
[Translation] The main purpose of the first phase: to compare the pharmacokinetic (PK) characteristics of HRG2010 and carbidopa sustained-release tablets after a single dose in patients with Parkinson's disease and symptom fluctuations;
The main purpose of the second phase: to evaluate the effectiveness of HRG2010 compared with carbidopa sustained-release tablets in the treatment of Parkinson's disease with symptom fluctuations.