Delving into the Latest Updates on LIM-0705 with Synapse

Overview

Basic Info

Drug Type

Small molecule drug

Synonyms

LIM 0705

Target

ABCA subfamily

Action

stimulants

Mechanism

ABCA subfamily stimulants, Insulin sensitizers

Therapeutic Areas

Endocrinology and Metabolic Disease

Active Indication-

Inactive Indication

Glucose IntoleranceInsulin Resistance

Originator Organization

Limerick BioPharma, Inc.

Active Organization-

Inactive Organization

Limerick BioPharma, Inc.

License Organization-

Drug Highest PhaseDiscontinuedPhase 2

First Approval Date-

Regulation-

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Preliminary research suggests that LIM-0705 improves insulin sensitivity with neutral effects on weight in obese and diabetic rodent models. Results from a Phase 1b clinical study, conducted in healthy volunteers, indicate that LIM-0705 and a major metabolite may be potential insulin sensitizers by OGTT.

Start Date01 May 2011

Sponsor / Collaborator

Limerick BioPharma, Inc.

NCT01093677

/ WithdrawnPhase 1

A Single-Blind,Randomized,Placebo-Controlled Phase 1 Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Exploratory Pharmacodynamics of LIM-0705 in Male Subjects With Impaired Glucose Tolerance

LIM-0705 will gain results on the effects of LIM-0705 on Male Subjects with Impaired Glucose Tolerance

Start Date01 Mar 2010

Sponsor / Collaborator

Limerick BioPharma, Inc.

NCT01060475

/ CompletedPhase 1

A Randomized, Double-Blind, Placebo-Controlled Phase 1 Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Exploratory Pharmacodynamics of LIM-0705 Given With or Without Tacrolimus in Healthy Male Subjects

LIM-0705 dosed separately and in combination with tacrolimus will be safe and well tolerated.

Start Date01 Feb 2010

Sponsor / Collaborator

Limerick BioPharma, Inc.

100 Clinical Results associated with LIM-0705

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100 Translational Medicine associated with LIM-0705

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100 Patents (Medical) associated with LIM-0705

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100 Deals associated with LIM-0705

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