Last update 04 Nov 2024

Doxofylline

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Ansimar, Doxofylline (USAN/INN), Doxofylline and Glucose
+ [30]
Mechanism
A2aR antagonists(Adenosine A2a receptor antagonists), PDE inhibitors, PDE2A inhibitors(Phosphodiesterase 2A inhibitors)
Inactive Indication
Originator Organization-
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
IT (01 Oct 1988),
RegulationOrphan Drug (US)
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Structure

Molecular FormulaC11H14N4O4
InChIKeyHWXIGFIVGWUZAO-UHFFFAOYSA-N
CAS Registry69975-86-6

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Pulmonary Disease, Chronic Obstructive
PH
-27 Apr 2007
Bronchitis
IT
10 Dec 2001
Asthma
IT
-01 Oct 1988
Bronchitis, Chronic
IT
-01 Oct 1988
Developing
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IndicationHighest PhaseCountry/LocationOrganizationDate
BronchiectasisPreclinical
US
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
227
Doxofylline 400 mg t.i.d
xdhjpvxuhy(djinogzcji) = 10% latosjurws (ymjyxkhogd )
Positive
28 Sep 2019
Not Applicable
-
ilalatvnvy(lzrsxagylq) = pmxxwqmgjf puyvmcabac (wqlmeeascw )
-
01 Sep 2014
ilalatvnvy(lzrsxagylq) = esjbolrhuq puyvmcabac (wqlmeeascw )
Not Applicable
30
Doxofylline 400 mg bid + inhaled bronchodilators
ypiguuyobk(xoolewijhd) = lzrmjdtnua yvibwhnvbg (xhtzlbszed )
Positive
01 Sep 2011
inhaled bronchodilators only
ypiguuyobk(xoolewijhd) = ihopbcjlfi yvibwhnvbg (xhtzlbszed )
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Approval

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Regulation

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