Drug Type Small molecule drug |
Synonyms Ansimar, Doxofylline (USAN/INN), Doxofylline and Glucose + [29] |
Target |
Mechanism A2aR antagonists(Adenosine A2a receptor antagonists), PDE inhibitors, PDE2A inhibitors(Phosphodiesterase 2A inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization- |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date IT (01 Oct 1988), |
RegulationOrphan Drug (US) |
Molecular FormulaC11H14N4O4 |
InChIKeyHWXIGFIVGWUZAO-UHFFFAOYSA-N |
CAS Registry69975-86-6 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D03898 | Doxofylline |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Bronchitis | IT | 10 Dec 2001 | |
Asthma | IT | - | 01 Oct 1988 |
Bronchitis, Chronic | IT | - | 01 Oct 1988 |
Pulmonary Disease, Chronic Obstructive | IT | - | 01 Oct 1988 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Bronchiectasis | Preclinical | US | - |
Not Applicable | 227 | Doxofylline 400 mg t.i.d | apqbjfcxkj(uzbhuahemh) = 10% aazkkdnjtb (kxealjbqfp ) View more | Positive | 28 Sep 2019 | ||
Not Applicable | - | pkrygclocl(ywbcidfrdp) = wfilrbryae dhiubfuong (hxisjmsezk ) | - | 01 Sep 2014 | |||
pkrygclocl(ywbcidfrdp) = vkfojdrmnd dhiubfuong (hxisjmsezk ) | |||||||
Not Applicable | 30 | Doxofylline 400 mg bid + inhaled bronchodilators | tjwadnhulb(hvpcypopsf) = dkzcnhzsxv bcwrplwwnb (olhrttawhz ) | Positive | 01 Sep 2011 | ||
inhaled bronchodilators only | tjwadnhulb(hvpcypopsf) = xuejqszmrk bcwrplwwnb (olhrttawhz ) |