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Clinical Trials associated with Fecal Microbiota Transplantation(Children's Hospital Los Angeles)Safety of FMT in Maintenance of Pediatric Crohn's Disease
The goal of this study is to evaluate the safety of Fecal Microbiota Transplantation (FMT) in children with Crohn's disease who are in remission. Safety will be the primary endpoint and Pediatric Crohn's Disease. Pediatric Crohn's Disease Activity Index (PCDAI) with other secondary endpoints including changes in gut microbial diversity will also be studied. All children will receive the equivalent of 50g of stools from a healthy donor into the jejunum through upper endoscopy. Also, 1-2 additional mucosal biopsies will be collected during patient's routine (standard of care) endoscopy. Subjects will have a total of 5 study visits within 24 weeks including phone call follow up on Day 7 after FMT.
100 Clinical Results associated with Fecal Microbiota Transplantation(Children's Hospital Los Angeles)
100 Translational Medicine associated with Fecal Microbiota Transplantation(Children's Hospital Los Angeles)
100 Patents (Medical) associated with Fecal Microbiota Transplantation(Children's Hospital Los Angeles)
100 Deals associated with Fecal Microbiota Transplantation(Children's Hospital Los Angeles)