Last update 25 Oct 2025

KA-5377

Overview

Basic Info

Drug Type
Bispecific antibody
Synonyms
KA 5377
Target
4-1BB x CD19
Action
agonists, inhibitors
Mechanism
4-1BB agonists(Tumor necrosis factor receptor superfamily member 9 agonists), CD19 inhibitors(B-lymphocyte antigen CD19 inhibitors)
Therapeutic Areas
NeoplasmsImmune System DiseasesHemic and Lymphatic Diseases
Active Indication
B-Cell Lymphoma
Inactive Indication-
Originator Organization
Kyinno Biotechnology Co., Ltd.Kyinno Biotechnology Co., Ltd.
Active Organization
Kyinno Biotechnology Co., Ltd.Kyinno Biotechnology Co., Ltd.
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with KA-5377
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100 Translational Medicine associated with KA-5377
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100 Patents (Medical) associated with KA-5377
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100 Deals associated with KA-5377
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
B-Cell LymphomaPreclinical
China
Kyinno Biotechnology Co., Ltd.Kyinno Biotechnology Co., Ltd.
29 Apr 2025
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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