Last update 09 May 2025

SHP-681

Overview

Basic Info

Drug Type
Fc fusion protein
Synonyms
GLP-2 Analog-Fc Fusion, SHP 681, TAK-681
Target
GLP-2R
Action
modulators
Mechanism
GLP-2R modulators(Glucagon-like peptide 2 receptor modulators)
Therapeutic Areas-
Active Indication-
Inactive Indication-
Originator Organization
Shire PlcShire Plc
Active Organization-
Inactive Organization
Shire PlcShire Plc
License Organization-
Drug Highest PhasePendingPhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with SHP-681
NCT03859323
/ CompletedPhase 1
A Randomized, Double-blind, Placebo-controlled, Phase 1 Study to Assess the Safety, Tolerability, and Pharmacokinetics of Ascending, Subcutaneous, Single and Multiple Doses of SHP681 (GLP-2 Analog-Fc Fusion) in Healthy Adult Subjects
100 Clinical Results associated with SHP-681
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100 Translational Medicine associated with SHP-681
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100 Patents (Medical) associated with SHP-681
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100 Deals associated with SHP-681
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R&D Status

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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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