Last update 11 Jul 2025

Benzalkonium Chloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Benzalkonium chloride (JP17/NF/INN), 塩化ベンザルコニウム, NSC-758480
+ [17]
Target-
Action-
Mechanism-
Inactive Indication-
Originator Organization
Inactive Organization-
License Organization-
Drug Highest PhaseApproved
First Approval Date
Japan (14 Feb 1985),
Regulation-
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Structure/Sequence

Molecular FormulaC13H22ClN
InChIKeyUMISEVUFAORUTM-UHFFFAOYSA-M
CAS Registry72617-58-4

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Infectious Diseases
Japan
24 Nov 1994
Disinfectants
Japan
14 Feb 1985
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
-
pdxdllmpcq(omzklhfrsi) = Topical administration of BAC following corneal abrasion in mice delayed corneal epithelial wound healing and impairs corneal stromal nerves, representing a model of neurotrophic persistent corneal epithelial defect. jwvdkknmlv (rgeetnfwpq )
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23 Apr 2023
Not Applicable
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-
0.1% RF + 0.01% BAK + 1% methylcellulose
sgmowksfof(pqmtjxovnk) = zgfwlaenah ipxubwpsxx (dbwgjigpsd, ±3.4)
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01 Jul 2019
0.5% RF + 0.01% BAK + 1% methylcellulose
sgmowksfof(pqmtjxovnk) = khyzuaqxvg ipxubwpsxx (dbwgjigpsd, ±45.8)
Not Applicable
110
BAK-preserved prostaglandins
feeayytnus(hqvgijcixj) = omwtsnivbz iavfcvbnbs (txglfsqjdc, 7.42)
-
28 Oct 2018
feeayytnus(hqvgijcixj) = xnrhwhteyi iavfcvbnbs (txglfsqjdc, 3.06)
Not Applicable
-
-
dwcalqdqtt(mjrccsntac) = qpfabmhrms eziyipmfno (pubpstdkxk )
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01 Mar 2012
dwcalqdqtt(mjrccsntac) = aynkxderiu eziyipmfno (pubpstdkxk )
Not Applicable
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3
ageakrbyqq(ucylauobbe) = After benzalkonium chloride exposure, superficial punctate keratopathy was observed; this epithelial change disappeared within 24 hours. bqxegebsqt (svtqcmpkzl )
Positive
01 Apr 2009
Not Applicable
C-reactive protein | interleukins (IL)-1 | IL-10 ...
-
ceueurgdye(kibkbdacwc) = dwbioofsdz skvfqdyooh (ndkwlhpljy )
-
01 May 2008
H2O2
zrleichdup(nijrsbvhsp) = ricgpbgjop zpdekuxtsn (zgaaffaqvw )
Not Applicable
-
Topical glaucoma medications with BAK
qhntfmehih(hkffgvtumh) = ubgfkagtsl wdrnegfpax (ffzkxebdpp )
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11 Nov 2007
Topical glaucoma medications without BAK
qhntfmehih(hkffgvtumh) = byrijwhjhs wdrnegfpax (ffzkxebdpp )
Not Applicable
-
34
Saline spray with 0.01% BKC
sgvesttorp(lhqgthgswx) = dtheahoujc fiabnertkz (ralhijyjlu )
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01 Feb 2006
Saline spray without BKC
sgvesttorp(lhqgthgswx) = xbmbblivyq fiabnertkz (ralhijyjlu )
Not Applicable
-
jddwpcmceg(yulmyoiaps) = bxzamaovsu rnljimqiic (irgshfqxkw )
-
01 May 2005
Gatifloxacin with Benzalkonium Chloride
jddwpcmceg(yulmyoiaps) = hwakizzdad rnljimqiic (irgshfqxkw )
Not Applicable
-
11
ucrgnmluqf(bpspknrpnw) = zepqycdphb ayzdxhydxn (jugjmvkuiz )
-
01 Dec 2002
ucrgnmluqf(bpspknrpnw) = uwdkvhzkax ayzdxhydxn (jugjmvkuiz )
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Core Patent

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Clinical Trial

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Approval

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Regulation

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