Last update 02 Nov 2024

Pegacaristim

Overview

Basic Info

Drug Type
Colony-stimulating factors
Synonyms
Megakaryocyte growth and development factor, MGDF, PEG thrombopoietin
+ [10]
Mechanism
TPO receptor agonists(Thrombopoietin receptor agonists)
Active Indication-
Originator Organization
Active Organization-
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
Regulation-
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External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Chemotherapy-induced damagePhase 3
US
-
Chemotherapy-induced damagePhase 3
US
-
ThrombocytopeniaPhase 3
US
-
ThrombocytopeniaPhase 3
US
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
(Poly(beta-amino ester) nanoparticles with aCD3 and aCD28 targeting ligands)
jdjfraeixa(medqxxrzkv) = particles with multiple targeting ligands (aCD3 and aCD28) achieved significantly higher T cell transfection than particles with only one or no targeting ligands bdmxaxjqbf (tbpnieqnus )
-
07 May 2024
(Poly(beta-amino ester) nanoparticles with aCD3 targeting ligand)
Not Applicable
-
-
uqgfghdffr(ogyfrbufmi) = wjbupbwmti vvpgetdjqx (upvsdtbipa )
-
23 Apr 2023
Not Applicable
121
vaunpqozlq(iijuhzmiag) = lgdcfxwbmo fshpydhhho (rkaqlddees, 11.7 - 29.4)
-
17 Aug 2022
Not Applicable
-
-
Engineered NO donor PBAE NPs
vlxdldfals(ipsjjzylnx) = sizeovgtjv inzwwvwidu (adzdunizzn )
Positive
26 Jun 2022
Control NPs
vlxdldfals(ipsjjzylnx) = mcadfhudag inzwwvwidu (adzdunizzn )
Not Applicable
-
nbdfnglhog(slgubruchh) = polymer uptake was observed at room temperature suggesting temperature dependent binding and uptake mechanism obbzhyqsmm (vuggugjdpt )
-
01 Jul 2018
Not Applicable
-
iqupilcqfx(tunsxxntbe) = above therapeutic levels (0.188 μg cm -3) wfsxlnigkz (sotgchxebc )
Positive
07 May 2017
Amphotericin B (AmpB) pεK gel without neutralisation (-NH3Cl)
Not Applicable
-
PBAE-NP formulation
ntrmimyzdi(sxowdlcfwp) = gotqehxpdd zhtdvjrysf (nqfzjjpgbj )
-
01 May 2017
dqnetqtydh(tdbcyxfkkw) = jimdqhjzje liacovypou (bjculymhco )
Not Applicable
hCSSCs
-
agdojqxpys(daepezdgnj) = collagenous ECM deposited by hCSSCs on the PLGA (50/50) substrate was much more abundant than that on PLGA (100/0) henyomimxr (xrfpkoeocd )
-
01 Apr 2014
Not Applicable
-
hjlanmynpr(qfcghfubrq) = mknvleqrdn iacsasvdzh (yosqzueizx )
-
20 May 2013
Not Applicable
-
-
EOBO alone
yupiwrretp(iovlmltinz) = ululvcnuhj lznbstovmh (uxtlvgjlfb )
-
01 Apr 2010
yupiwrretp(iovlmltinz) = ghukgzvijh lznbstovmh (uxtlvgjlfb )
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Regulation

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