Last update 31 Jan 2026

INV-8989

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
INV 8989, INV8989
Target
KRAS G12D
Action
degraders
Mechanism
KRAS G12D degraders(GTPase KRas G12D degraders)
Therapeutic Areas
Neoplasms
Active Indication
KRAS mutation-related tumors
Inactive Indication-
Originator Organization
Guangdong Innovative Drug Translational Medicine Research Institute Co., Ltd.Foshan Ionova Biotherapeutics Co., Ltd.
Active Organization
Foshan Ionova Biotherapeutics Co., Ltd.Guangdong Innovative Drug Translational Medicine Research Institute Co., Ltd.
Inactive Organization-
License Organization-
Drug Highest PhaseIND Application
First Approval Date-
Regulation-
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Related

100 Clinical Results associated with INV-8989
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100 Translational Medicine associated with INV-8989
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100 Patents (Medical) associated with INV-8989
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100 Deals associated with INV-8989
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
KRAS mutation-related tumorsIND Application
China
Foshan Ionova Biotherapeutics Co., Ltd.
26 Dec 2025
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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