Last update 04 Nov 2024

Mebeverine Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Mebeverine, Mebeverine hydrochloride (USAN), CSAG-144
+ [5]
Target
mAChRs
Mechanism
mAChRs antagonists(Muscarinic acetylcholine receptor antagonists)
Therapeutic Areas
Digestive System Disorders
Active Indication
GastrospasmIrritable Bowel Syndrome
Inactive Indication-
Originator Organization-
Active Organization-
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date-
Regulation-
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Structure

Molecular FormulaC25H36ClNO5
InChIKeyPLGQWYOULXPJRE-UHFFFAOYSA-N
CAS Registry2753-45-9

Related

16
Clinical Trials associated with Mebeverine Hydrochloride
IRCT20190706044111N37 / Suspended
A randomized, open label, single dose, crossover, bioequivalence study of Mebeverin 135mg tablet of Amin Pharm. Co., IRAN in comparison of Duspatalin 135mg tablet of Abbott in 24 healthy adult subjects under fasting condition
IRCT20210519051345N52 / RecruitingIIT
Fasted-state in vivo bioequivalence study of Mebeverine ER 200 mg capsule manufactured by AaniDarman Co. compared with innovator product
NCT05867550 / CompletedPhase 4IIT
To Compare the Efficacy of (Rifaximin + Mebeverine), (Rifaximin + Amitriptyline), and (Rifaximin + Psyllium Husk) in Irritable Bowel Syndrome Associated With Diarrhea
100 Clinical Results associated with Mebeverine Hydrochloride
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100 Translational Medicine associated with Mebeverine Hydrochloride
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100 Patents (Medical) associated with Mebeverine Hydrochloride
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205
Literatures (Medical) associated with Mebeverine Hydrochloride
01 Feb 2024Biotechnology journal
3D‐QSAR pharmacophore modeling, virtual screening, molecular docking, MD simulations, in vitro and in vivo studies to identify potential anti‐hyperplasia drugs
01 Jan 2024Sudebno-meditsinskaia ekspertiza
Development of selective method for identifying mebeverine in hair
01 Jan 2024Sudebno-meditsinskaia ekspertiza
Development of selective method for mebeverine detection in blood
100 Deals associated with Mebeverine Hydrochloride
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External Link

KEGGWikiATCDrug Bank
D04868Mebeverine Hydrochloride
A03AA04
DB12554

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Gastrospasm---
Irritable Bowel Syndrome---
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Clinical Result

Indication
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Regulation

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