Last update 12 Dec 2024
Mebeverine Hydrochloride
Last update 12 Dec 2024
Overview
Basic Info
Drug Type Small molecule drug |
Synonyms Mebeverine, Mebeverine hydrochloride (USAN), CSAG-144 + [5] |
Target |
Mechanism mAChRs antagonists(Muscarinic acetylcholine receptor antagonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization- |
Active Organization |
Inactive Organization- |
Drug Highest PhaseApproved |
First Approval Date AU (28 Aug 2001), |
Regulation- |
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Structure
Molecular FormulaC25H36ClNO5 |
InChIKeyPLGQWYOULXPJRE-UHFFFAOYSA-N |
CAS Registry2753-45-9 |
Related
15
Clinical Trials associated with Mebeverine HydrochlorideA randomized, open label, single dose, crossover, bioequivalence study of Mebeverin 135mg tablet of Amin Pharm. Co., IRAN in comparison of Duspatalin 135mg tablet of Abbott in 24 healthy adult subjects under fasting condition
Fasted-state in vivo bioequivalence study of Mebeverine ER 200 mg capsule manufactured by AaniDarman Co. compared with innovator product
To Compare the Efficacy of (Rifaximin + Mebeverine), (Rifaximin + Amitriptyline), and (Rifaximin + Psyllium Husk) in Irritable Bowel Syndrome Associated With Diarrhea
100 Clinical Results associated with Mebeverine Hydrochloride
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100 Translational Medicine associated with Mebeverine Hydrochloride
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100 Patents (Medical) associated with Mebeverine Hydrochloride
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206
Literatures (Medical) associated with Mebeverine Hydrochloride01 Feb 2024Biotechnology journal
3D‐QSAR pharmacophore modeling, virtual screening, molecular docking, MD simulations, in vitro and in vivo studies to identify potential anti‐hyperplasia drugs
Article
Author: Akbar, Muhammad Yasir ; Khan, Dildar ; Wang, Hao ; Haq, Ihsan-Ul ; Chen, Jian-Zhong ; Khan, Muhammad Zafar Irshad
01 Jan 2024Sudebno-meditsinskaia ekspertiza
Development of selective method for identifying mebeverine in hair
Article
Author: Balabanova, O L ; Vikman, P S ; Strelova, O Yu ; Grebenyuk, A N
01 Jan 2024Sudebno-meditsinskaia ekspertiza
Development of selective method for mebeverine detection in blood
Article
Author: Balabanova, O L ; Vikman, P S ; Strelova, O Yu ; Grebenyuk, A N
100 Deals associated with Mebeverine Hydrochloride
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External Link
| KEGG | Wiki | ATC | Drug Bank |
|---|---|---|---|
| D04868 | Mebeverine Hydrochloride |
R&D Status
10 top approved records. to view more data
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| Indication | Country/Location | Organization | Date |
|---|---|---|---|
| Abdominal Pain | AU | 28 Aug 2001 | |
| Diarrhea | AU | 28 Aug 2001 | |
| Flatulence | AU | 28 Aug 2001 | |
| Muscle Cramp | AU | 28 Aug 2001 | |
| Irritable Bowel Syndrome | AU | 28 Aug 2001 | |
| Gastrospasm | - | - | - |
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