Last update 13 Dec 2025

Macromolecular carrier-linked carbon monoxide releasing molecules (Alfama)

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
macromolecular carrier-linked carbon monoxide releasing molecules (Alfama), ALF-421
Target
TNF
Action
inhibitors
Mechanism
TNF inhibitors(Tumor necrosis factor inhibitors)
Therapeutic Areas
NeoplasmsDigestive System DisordersOther Diseases
Active Indication-
Inactive Indication
IleusInflammationLiver Failure, Acute+ [2]
Originator Organization
Alfama, Inc.Alfama, Inc.
Active Organization-
Inactive Organization
Alfama, Inc.Alfama, Inc.
Proterris, Inc.Proterris, Inc.
License Organization-
Drug Highest PhaseDiscontinuedPreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with Macromolecular carrier-linked carbon monoxide releasing molecules (Alfama)
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100 Translational Medicine associated with Macromolecular carrier-linked carbon monoxide releasing molecules (Alfama)
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100 Patents (Medical) associated with Macromolecular carrier-linked carbon monoxide releasing molecules (Alfama)
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100 Deals associated with Macromolecular carrier-linked carbon monoxide releasing molecules (Alfama)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Liver Failure, AcutePreclinical
United States
Proterris, Inc.Proterris, Inc.
-
Metabolic Dysfunction Associated SteatohepatitisPreclinical
United States
Proterris, Inc.Proterris, Inc.
-
NeoplasmsPreclinical
United States
Proterris, Inc.Proterris, Inc.
-
IleusDiscovery
United States
Alfama, Inc.Alfama, Inc.
-
InflammationDiscovery
Portugal
Alfama, Inc.Alfama, Inc.
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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