Last update 22 Nov 2025

YOLT-202

Overview

Basic Info

Drug Type
Gene editing
Synonyms
YOLT 202, YOLT202
Target
A1AT
Action
modulators
Mechanism
A1AT modulators(Alpha-1-antiproteinase modulators)
Therapeutic Areas
Congenital DisordersDigestive System DisordersRespiratory Diseases+ [1]
Active Indication
Alpha 1-Antitrypsin Deficiency
Inactive Indication-
Originator Organization
Yoltech Therapeutics Co., Ltd.Yoltech Therapeutics Co., Ltd.
Active Organization
Shanghai Renji HospitalShanghai Renji HospitalYoltech Therapeutics Co., Ltd.Yoltech Therapeutics Co., Ltd.
Inactive Organization-
License Organization-
Drug Highest PhaseEarly Phase 1
First Approval Date-
RegulationOrphan Drug (United States)
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Related

2
Clinical Trials associated with YOLT-202
ChiCTR2500105922
/ Not yet recruitingNot ApplicableIIT
Clinical Exploratory Study of YOLT-202 in the Treatment of Alpha-1 Antitrypsin Deficiency (AATD)
NCT07193615
/ Active, not recruitingEarly Phase 1IIT
Clinical Exploratory Study of YOLT-202 in the Treatment of Alpha-1 Antitrypsin Deficiency (AATD)
100 Clinical Results associated with YOLT-202
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100 Translational Medicine associated with YOLT-202
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100 Patents (Medical) associated with YOLT-202
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100 Deals associated with YOLT-202
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Alpha 1-Antitrypsin DeficiencyPhase 1
China
Shanghai Renji HospitalShanghai Renji Hospital
18 Jun 2025
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Approval

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Regulation

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