Last update 05 Apr 2025

huMNC2-CAR44 T cells(Minerva Biotechnologies)

Overview

Basic Info

Drug Type
Autologous CAR-T
Synonyms
CAR T therapeutics - Minerva, huMNC2-CAR44 T cells - Minerva Biotechnologies, huMNC2-scFv-CAR T cells
Target
MUC1
Action
modulators
Mechanism
MUC1 modulators(Mucin-1 modulators)
Therapeutic Areas
NeoplasmsSkin and Musculoskeletal Diseases
Active Indication
Advanced breast cancerMetastatic human epidermal growth factor 2 positive carcinoma of breast
Inactive Indication-
Originator Organization
Minerva Biotechnologies Corp.Minerva Biotechnologies Corp.
Active Organization
Minerva Biotechnologies Corp.Minerva Biotechnologies Corp.
Inactive Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with huMNC2-CAR44 T cells(Minerva Biotechnologies)
NCT04020575
/ RecruitingPhase 1
Adoptive Immunotherapy for Advanced MUC1* Positive Breast Cancer With Autologous T Cells Engineered to Express a Chimeric Antigen Receptor, huMNC2-CAR44 or huMNC2-CAR22, Specific for a Cleaved Form of MUC1 (MUC1*)
100 Clinical Results associated with huMNC2-CAR44 T cells(Minerva Biotechnologies)
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100 Translational Medicine associated with huMNC2-CAR44 T cells(Minerva Biotechnologies)
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100 Patents (Medical) associated with huMNC2-CAR44 T cells(Minerva Biotechnologies)
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100 Deals associated with huMNC2-CAR44 T cells(Minerva Biotechnologies)
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced breast cancerPhase 1
United States
Minerva Biotechnologies Corp.Minerva Biotechnologies Corp.
15 Jan 2020
Metastatic human epidermal growth factor 2 positive carcinoma of breastPhase 1
United States
Minerva Biotechnologies Corp.Minerva Biotechnologies Corp.
15 Jan 2020
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Clinical Result

Indication
Phase
Evaluation
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Clinical Trial

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Approval

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Regulation

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