Last update 29 May 2025

Danoprevir Sodium/Ritonavir

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms-
Target
HIV-1 pol x NS3/NS4A
Action
inhibitors
Mechanism
HIV-1 pol inhibitors(Human immunodeficiency virus type 1 Pol protein inhibitors), NS3/NS4A inhibitors(Hepatitis C virus serine protease, NS3/NS4A inhibitors)
Therapeutic Areas
Infectious DiseasesDigestive System Disorders
Active Indication
Hepatitis C
Inactive Indication
Chronic hepatitis C genotype 1Fibrosis
Originator Organization
F. Hoffmann-La Roche Ltd.
Active Organization
F. Hoffmann-La Roche Ltd.
Inactive Organization
Hoffmann-La Roche, Inc.
License Organization-
Drug Highest PhasePhase 3
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC37H48N6O5S2
InChIKeyNCDNCNXCDXHOMX-XGKFQTDJSA-N
CAS Registry155213-67-5
View All Structures (2)

Related

2
Clinical Trials associated with Danoprevir Sodium/Ritonavir
ChiCTR2000030259
/ RecruitingNot ApplicableIIT
Evaluation Danoprevir sodium tablets combined with ritonavir in the treatment of novel coronavirus infection (COVID-19): a randomized, open and controlled trial
NCT01749150
/ CompletedPhase 2
STUDY TO EVALUATE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND ANTIVIRAL ACTIVITY OF RITONAVIR-BOOSTED DANOPREVIR IN COMBINATION WITH PEGINTERFERON ALFA-2A PLUS RIBAVIRIN IN TREATMENT-NAÏVE PATIENTS OF ASIAN ORIGIN WHO HAVE CHRONIC HEPATITIS C GENOTYPE 1 WITH OR WITHOUT COMPENSATED CIRRHOSIS
100 Clinical Results associated with Danoprevir Sodium/Ritonavir
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100 Translational Medicine associated with Danoprevir Sodium/Ritonavir
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100 Patents (Medical) associated with Danoprevir Sodium/Ritonavir
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100 Deals associated with Danoprevir Sodium/Ritonavir
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hepatitis CPhase 3-
F. Hoffmann-La Roche Ltd.
-
Chronic hepatitis C genotype 1Phase 2
United States
Hoffmann-La Roche, Inc.
01 Apr 2013
Chronic hepatitis C genotype 1Phase 2
Taiwan Province
Hoffmann-La Roche, Inc.
01 Apr 2013
Chronic hepatitis C genotype 1Phase 2
Thailand
Hoffmann-La Roche, Inc.
01 Apr 2013
FibrosisPhase 2
United States
Hoffmann-La Roche, Inc.
01 Apr 2013
FibrosisPhase 2
Taiwan Province
Hoffmann-La Roche, Inc.
01 Apr 2013
FibrosisPhase 2
Thailand
Hoffmann-La Roche, Inc.
01 Apr 2013
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Clinical Trial

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Approval

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Regulation

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