Last update 24 May 2025

IMD-2358

Overview

Basic Info

Drug Type
Antibody drug conjugate (ADC)
Synonyms
IMD 2358, IMD2358
Target
ROR1 x TLR7 x TLR8 x Top I
Action
antagonists, agonists, inhibitors
Mechanism
ROR1 antagonists(Inactive tyrosine-protein kinase transmembrane receptor ROR1 antagonists), TLR7 agonists(Toll like receptor 7 agonists), TLR8 agonists(Toll like receptor 8 agonists)
Therapeutic Areas
Neoplasms
Active Indication
Solid tumor
Inactive Indication-
Originator Organization
Shanghai Affinity Biopharmaceutical Co., Ltd.Shanghai Affinity Biopharmaceutical Co., Ltd.
Active Organization
Shanghai Affinity Biopharmaceutical Co., Ltd.Shanghai Affinity Biopharmaceutical Co., Ltd.
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC26H24FN3O6
InChIKeyPLXLYXLUCNZSAA-QLXKLKPCSA-N
CAS Registry1599440-33-1
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Related

100 Clinical Results associated with IMD-2358
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100 Translational Medicine associated with IMD-2358
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100 Patents (Medical) associated with IMD-2358
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100 Deals associated with IMD-2358
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Solid tumorPreclinical
China
Shanghai Affinity Biopharmaceutical Co., Ltd.Shanghai Affinity Biopharmaceutical Co., Ltd.
01 May 2025
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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