Delving into the Latest Updates on BEBT-507 with Synapse

Overview

Basic Info

Drug Type

siRNA

Synonyms

Target

TMPRSS6

Action

inhibitors

Mechanism

TMPRSS6 inhibitors(Transmembrane protease serine 6 inhibitors)

Therapeutic Areas

NeoplasmsHemic and Lymphatic DiseasesOther Diseases+ [1]

Active Indication

Polycythemia VeraIron Metabolism Disorders

Inactive Indication-

Originator Organization

BeBetter Med, Inc.

Active Organization

BeBetter Med, Inc.

Inactive Organization-

License Organization-

Drug Highest PhasePhase 1

First Approval Date-

Regulation-

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Structure/Sequence

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Ⅰa期临床研究主要目的：评价BEBT-507在真性红细胞增多症（PV）患者的安全性和耐受性；次要目的：评价BEBT-507在真性红细胞增多症（PV）患者中的有效性；评价BEBT-507药代动力学（PK）和药效动力学（PD）特征；为BEBT-507在真性红细胞增多症（PV）患者中的Ⅰb期临床试验提供推荐剂量。 Ⅰb期临床研究主要目的：评价BEBT-507在真性红细胞增多症（PV）患者中的有效性；次要目的：评价BEBT-507在真性红细胞增多症（PV）患者中安全性和耐受性；评价BEBT-507药代动力学（PK）特征；为BEBT-507在真性红细胞增多症（PV）患者中的Ⅲ期临床试验提供推荐剂量。

[Translation]

Phase Ia clinical study Main purpose: To evaluate the safety and tolerability of BEBT-507 in patients with polycythemia vera (PV); Secondary purpose: To evaluate the efficacy of BEBT-507 in patients with polycythemia vera (PV); To evaluate the pharmacokinetic (PK) and pharmacodynamic (PD) characteristics of BEBT-507; To provide a recommended dose for the Phase Ib clinical trial of BEBT-507 in patients with polycythemia vera (PV). Phase Ib clinical study Main purpose: To evaluate the efficacy of BEBT-507 in patients with polycythemia vera (PV); Secondary purpose: To evaluate the safety and tolerability of BEBT-507 in patients with polycythemia vera (PV); To evaluate the pharmacokinetic (PK) characteristics of BEBT-507; To provide a recommended dose for the Phase III clinical trial of BEBT-507 in patients with polycythemia vera (PV).

Start Date-

Sponsor / Collaborator

BeBetter Med, Inc.

100 Clinical Results associated with BEBT-507

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100 Translational Medicine associated with BEBT-507

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100 Patents (Medical) associated with BEBT-507

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100 Deals associated with BEBT-507

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