Last update 08 May 2025

VU6010608

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms-
Target
mGluR7
Action
modulators
Mechanism
mGluR7 modulators(Metabotropic glutamate receptor 7 modulators)
Therapeutic Areas
Nervous System Diseases
Active Indication-
Inactive Indication
Central Nervous System Diseases
Originator Organization
Vanderbilt UniversityVanderbilt University
Active Organization-
Inactive Organization
Vanderbilt UniversityVanderbilt University
License Organization-
Drug Highest PhasePendingPreclinical
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC18H15F3N4O4
InChIKeyYCDOKDADFOBKIL-UHFFFAOYSA-N
CAS Registry2165325-42-6

Related

100 Clinical Results associated with VU6010608
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100 Translational Medicine associated with VU6010608
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100 Patents (Medical) associated with VU6010608
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3
Literatures (Medical) associated with VU6010608
01 Oct 2022Bioorganic & Medicinal Chemistry Letters
Development and profiling of mGlu7 NAMs with a range of saturable inhibition of agonist responses in vitro
14 Feb 2019Journal of Medicinal ChemistryQ1 · MEDICINE
Discovery of an Orally Bioavailable and Central Nervous System (CNS) Penetrant mGlu7 Negative Allosteric Modulator (NAM) in Vivo Tool Compound: N-(2-(1H-1,2,4-triazol-1-yl)-5-(trifluoromethoxy)phenyl)-4-(cyclopropylmethoxy)-3-methoxybenzamide (VU6012962)
Q1 · MEDICINE
14 Dec 2017ACS Medicinal Chemistry LettersQ3 · MEDICINE
VU6010608, a Novel mGlu7 NAM from a Series of N-(2-(1H-1,2,4-Triazol-1-yl)-5-(trifluoromethoxy)phenyl)benzamides
Q3 · MEDICINE
100 Deals associated with VU6010608
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Central Nervous System DiseasesPreclinical
United States
Vanderbilt UniversityVanderbilt University
10 Nov 2017
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Clinical Result

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Approval

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Regulation

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