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Last update 09 May 2025
Kunxinning Granules
Last update 09 May 2025
Overview
Basic Info
Drug Type Herbal medicine |
Synonyms Kunyining Granules, 坤怡宁颗粒 |
Target- |
Action- |
Mechanism- |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhaseApproved |
First Approval Date China (24 Nov 2021), |
Regulation- |
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Related
3
Clinical Trials associated with Kunxinning GranulesCTR20240383
坤心宁颗粒治疗更年期综合征（肾阴阳两虚证）安全性和有效性的多中心Ⅳ期临床试验
[Translation] A multicenter phase IV clinical trial on the safety and efficacy of Kunxinning granules in the treatment of menopausal syndrome (kidney yin and yang deficiency syndrome)
CTR20140270
坤怡宁颗粒治疗围绝经期综合征（肾阴阳两虚证）随机、双盲单模拟、安慰剂平行对照、多中心Ⅱ期临床试验
[Translation] A randomized, double-blind, single-dummy, placebo-controlled, multicenter phase II clinical trial of Kunyining granules in the treatment of perimenopausal syndrome (kidney yin and yang deficiency syndrome)
CTR20140289
坤怡宁颗粒治疗更年期综合征(肾阴阳两虚证)评价其有效性和安全性的随机、双盲、安慰剂对照、多中心临床试验
[Translation] A randomized, double-blind, placebo-controlled, multicenter clinical trial to evaluate the efficacy and safety of Kunyining granules in the treatment of menopausal syndrome (deficiency of both kidney yin and yang syndrome)
100 Clinical Results associated with Kunxinning Granules
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100 Translational Medicine associated with Kunxinning Granules
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100 Patents (Medical) associated with Kunxinning Granules
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1
Literatures (Medical) associated with Kunxinning Granules01 Jul 2006Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
[Effect of Kunyining capsule on reproductive endocrine-immune functions in ovariectomized rats].
Article
Author: Yang, Ming-hua ; Yang, Su-bei ; Long, Sen ; Jin, Jie ; Jin, Zu-han
OBJECTIVE:
To study the therapeutic mechanism of Kunyining (KYN) on the climacteric syndrome and provide the pharmacodynamic basis.
METHOD:
Ovariectomized rats were used as model to observe the effect of KYN on weight and the index of the organ of OVX rats. The concentration of E2, FSH, LH, PRL, BGP and IL-2 in serum were measured by competitive radio-immunological methods.
RESULT:
KYN could obviously increase the index of uterus and adrenal gland in OVX rats, and enhance the contents of E2, IL-2 and BGP. The level of FSH, LH, PRL in serum were decreased.
CONCLUSION:
KYN can regulate beneficially the unbalanced reproductive endocrine-immune network, which is the pharmacological basis of KYN treating climacteric syndrome.
100 Deals associated with Kunxinning Granules
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R&D Status
10 top approved records. to view more data
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| Indication | Country/Location | Organization | Date |
|---|---|---|---|
| Menopausal syndrome | China | 24 Nov 2021 |
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