Last update 20 Jul 2026

GPR68 program(Cumulus Oncology)

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
GPR68 (OGR1) negative allosteric modulator(Cumulus Oncology)
Target
GPR68
Action
modulators
Mechanism
GPR68 modulators(G protein-coupled receptor 68 modulators)
Therapeutic Areas
NeoplasmsImmune System DiseasesDigestive System Disorders+ [1]
Active Indication
Colitis, UlcerativeFibrosisInflammation+ [1]
Inactive Indication-
Originator Organization
Cumulus Oncology Ltd.Cumulus Oncology Ltd.
Active Organization
leadXpro AGleadXpro AG
Cumulus Oncology Ltd.Cumulus Oncology Ltd.GIO Therapeutics AG
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with GPR68 program(Cumulus Oncology)
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100 Translational Medicine associated with GPR68 program(Cumulus Oncology)
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100 Patents (Medical) associated with GPR68 program(Cumulus Oncology)
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100 Deals associated with GPR68 program(Cumulus Oncology)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Colitis, UlcerativePreclinical
Switzerland
leadXpro AGleadXpro AG
18 Feb 2026
Colitis, UlcerativePreclinical
United Kingdom
Cumulus Oncology Ltd.Cumulus Oncology Ltd.
18 Feb 2026
FibrosisPreclinical
Switzerland
leadXpro AGleadXpro AG
01 Nov 2025
FibrosisPreclinical
United Kingdom
Cumulus Oncology Ltd.Cumulus Oncology Ltd.
01 Nov 2025
InflammationPreclinical
Switzerland
leadXpro AGleadXpro AG
20 Aug 2024
InflammationPreclinical
Switzerland
GIO Therapeutics AG
20 Aug 2024
NeoplasmsPreclinical
Switzerland
GIO Therapeutics AG
20 Aug 2024
NeoplasmsPreclinical
Switzerland
leadXpro AGleadXpro AG
20 Aug 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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