Last update 09 Dec 2025

LV091

Overview

Basic Info

Drug Type
in vivo CAR-T therapy
Synonyms
LV-091, PG011
Target
CD19 x PD-1
Action
inhibitors
Mechanism
CD19 inhibitors(B-lymphocyte antigen CD19 inhibitors), PD-1 inhibitors(Programmed cell death protein 1 inhibitors)
Therapeutic Areas
Immune System Diseases
Active Indication
Autoimmune Diseases
Inactive Indication-
Originator Organization
PersonGenAnke Cellular Therapeutics Co., Ltd.PersonGenAnke Cellular Therapeutics Co., Ltd.
Active Organization
PersonGenAnke Cellular Therapeutics Co., Ltd.PersonGenAnke Cellular Therapeutics Co., Ltd.PersonGen BioTherapeutics (Suzhou) Co., Ltd.PersonGen BioTherapeutics (Suzhou) Co., Ltd.
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

2
Clinical Trials associated with LV091
ChiCTR2400081767
/ CompletedPhase 2IIT
A multicenter, randomized, double-blind, placebo-controlled dose-exploratory Phase II study to evaluate the safety, efficacy, and pharmacokinetic profile of PG-011 nasal spray in participants with moderate-to-severe seasonal allergic rhinitis
ChiCTR2300075459
/ CompletedPhase 1IIT
A randomized, double-blind, placebo-controlled, dose-escalation phase I clinical study to evaluate the safety, tolerability, and pharmacokinetic profile of PG-011 nasal spray after single and multiple doses in healthy adult participants
100 Clinical Results associated with LV091
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100 Translational Medicine associated with LV091
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100 Patents (Medical) associated with LV091
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100 Deals associated with LV091
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Autoimmune DiseasesPreclinical
China
PersonGen BioTherapeutics (Suzhou) Co., Ltd.PersonGen BioTherapeutics (Suzhou) Co., Ltd.
14 Nov 2025
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Clinical Result

Indication
Phase
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Clinical Trial

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Approval

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Regulation

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