Delving into the Latest Updates on Hib-DTaP-poliovirus vaccine(Statens Serum Institute) with Synapse

Overview

Basic Info

Drug Type

Combination vaccine, Prophylactic vaccine, Toxoid vaccine

Synonyms

Certiva-IPV-Hib, CertivaTM-IPV-Hib, DTaP-IPV-Hib

+ [3]

Target-

Action

stimulants

Mechanism

Immunostimulants

Therapeutic Areas

Infectious DiseasesNervous System DiseasesRespiratory Diseases+ [1]

Active Indication-

Inactive Indication

DiphtheriaHaemophilus InfectionsPoliomyelitis+ [2]

Originator Organization

Statens Serum Institute

Active Organization-

Inactive Organization

Statens Serum Institute

License Organization-

Drug Highest PhasePendingClinical

First Approval Date-

Regulation-

The uniform use in Canada of a single Haemophilus influenzae type b conjugate vaccine in combination with diphtheria, tetanus, acellular pertussis, and inactivated poliovirus vaccines (DTaP.IPV/Hib) facilitates ongoing assessment of vaccine effectiveness, including any effects of recently added concurrent vaccinations and increasing time since vaccination. Surveillance at 12 pediatric centers in 2004-2007 indicates that vaccine failures remain rare and case totals approach an irreducible minimum, with no age shift.

01 Mar 2006·VaccineQ3 · MEDICINE

Assessment of the compatibility of co-administered 7-valent pneumococcal conjugate, DTaP.IPV/PRP-T Hib and hepatitis B vaccines in infants 2–7 months of age

Q3 · MEDICINE

Article

Author: Jan Ochnio ; Bruce Smith ; David W. Scheifele ; Keith Meloff ; Denzyl Duarte-Monteiro ; Scott A. Halperin

This study assessed compatibility of concurrently administered 7-valent pneumococcal conjugate (PCV7), hepatitis B (HB) and DTaP.IPV/Hib vaccines. Infants were given DTaP.IPV/Hib and HB at 2, 4, 6 months and randomly assigned (2:1) to receive PCV7 concurrently or sequentially (at 3, 5, 7 months). Antibody levels were compared in 246 concurrent and 122 sequential vaccinees. Responses to PCV7, DTaP.IPV/Hib and HB were generally unaltered with concurrent administration except that Hib responses were increased (p=0.008) and HB responses were reduced (p=0.006) with concurrent dosing, the latter possibly from same thigh injection with DTaP.IPV/Hib. We conclude that PCV7, DTaP.IPV/Hib and HB are compatible with concurrent, separate injections.

100 Deals associated with Hib-DTaP-poliovirus vaccine(Statens Serum Institute)

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