Last update 20 Mar 2025

Fosinopril Sodium/Hydrochlorothiazide

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
MONOPRIL-HCT
Target
ACE x NCC
Action
inhibitors
Mechanism
ACE inhibitors(Angiotensin-converting enzyme inhibitors), NCC inhibitors(Thiazide-sensitive sodium-chloride cotransporter inhibitors)
Therapeutic Areas
Cardiovascular Diseases
Active Indication
Hypertension
Inactive Indication
Angioedema
Originator Organization
Bristol Myers Squibb Co.Bristol Myers Squibb Co.
Active Organization
Arrotex Pharmaceuticals Pty Ltd.Arrotex Pharmaceuticals Pty Ltd.Startup
Inactive Organization
Bristol Myers Squibb Co.Bristol Myers Squibb Co.
Drug Highest PhaseApproved
First Approval Date
United States (30 Nov 1994),
Angioedema
Regulation-
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Structure/Sequence

Molecular FormulaC7H8ClN3O4S2
InChIKeyJZUFKLXOESDKRF-UHFFFAOYSA-N
CAS Registry58-93-5
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Related

2
Clinical Trials associated with Fosinopril Sodium/Hydrochlorothiazide
NCT00777972
/ CompletedNot Applicable
A Bioequivalence Study of Test and Reference Fosinopril Sodium/ Hydrochlorothiazide 20/12.5 mg Tablets Under Fasting Conditions
NCT00778713
/ CompletedNot Applicable
A Bioequivalence Study of Test and Reference Fosinopril Sodium/ Hydrochlorothiazide 20/ 12.5 mg Tablets Under Non-Fasting Conditions
100 Clinical Results associated with Fosinopril Sodium/Hydrochlorothiazide
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100 Translational Medicine associated with Fosinopril Sodium/Hydrochlorothiazide
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100 Patents (Medical) associated with Fosinopril Sodium/Hydrochlorothiazide
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100 Deals associated with Fosinopril Sodium/Hydrochlorothiazide
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External Link

KEGGWikiATCDrug Bank
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C09BA09
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R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Hypertension
Australia
Arrotex Pharmaceuticals Pty Ltd.Arrotex Pharmaceuticals Pty Ltd.Startup
19 Aug 2008
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Approval

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Regulation

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