Last update 21 Jun 2025

GMB-101

Overview

Basic Info

Drug Type
Proteolysis-targeting chimeras (PROTAC)
Synonyms
GMB-101
Target
Bcr-Abl
Action
inhibitors
Mechanism
Bcr-Abl inhibitors(Bcr-Abl tyrosine kinase inhibitors)
Therapeutic Areas
NeoplasmsHemic and Lymphatic Diseases
Active Indication-
Inactive Indication
Philadelphia chromosome positive chronic myelogenous leukemia
Originator Organization
Yale UniversityYale University
Active Organization-
Inactive Organization
Yale UniversityYale University
License Organization-
Drug Highest PhasePendingPreclinical
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC44H47F3N8O7S
InChIKeyDTXGFSWBHDABPE-MNYREFGISA-N
CAS Registry2489876-12-0

Related

100 Clinical Results associated with GMB-101
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100 Translational Medicine associated with GMB-101
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100 Patents (Medical) associated with GMB-101
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100 Deals associated with GMB-101
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Philadelphia chromosome positive chronic myelogenous leukemiaPreclinical
United States
Yale UniversityYale University
13 Sep 2019
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Clinical Result

Indication
Phase
Evaluation
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Deal

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Clinical Trial

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Approval

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Regulation

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