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Clinical Trials associated with HR-1801注射用 HR1801 在健康受试者中的安全性、耐受性和药代动力学特征的I 期临床研究
[Translation] Phase I clinical study on the safety, tolerability and pharmacokinetic characteristics of HR1801 for injection in healthy subjects
1)评估注射用HR1801 LD/CR 静脉给药24 h 在中国健康受试者中的安全性与耐受性。
2)评估注射用HR1801 LD/CR 静脉给药24 h 在中国健康受试者中的药代动力学(PK)特征。
3)探索并确定一个基于数据和模型推导的HR1801 给药方案,该方案预计可安全实现术后镇痛。
4)评估酮咯酸氨丁三醇注射液静脉给药在中国健康受试者中的安全性与耐受性。
5)评估酮咯酸氨丁三醇注射液静脉给药在中国健康受试者中的PK 特征。
6)初步比较注射用HR1801 采用LD/CR 静脉给药的方式与酮咯酸氨丁三醇注射液每6 h(q6h)静脉推注给药的PK 特征。
[Translation] 1) Evaluate the safety and tolerability of 24 h intravenous administration of HR1801 LD/CR for injection in healthy Chinese subjects.
2) Evaluate the pharmacokinetic (PK) characteristics of 24 h intravenous administration of HR1801 LD/CR for injection in healthy Chinese subjects.
3) Explore and determine a data- and model-derived HR1801 dosing regimen that is expected to safely achieve postoperative analgesia.
4) Evaluate the safety and tolerability of intravenous administration of ketorolac tromethamine injection in healthy Chinese subjects.
5) Evaluate the PK characteristics of intravenous administration of ketorolac tromethamine injection in healthy Chinese subjects.
6) Preliminary comparison of the PK characteristics of LD/CR intravenous administration of HR1801 for injection with intravenous push administration of ketorolac tromethamine injection every 6 hours (q6h).
100 Clinical Results associated with HR-1801
100 Translational Medicine associated with HR-1801
100 Patents (Medical) associated with HR-1801
100 Deals associated with HR-1801