Last update 08 May 2025

ONO-2808

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Target
S1PR5
Action
agonists
Mechanism
S1PR5 agonists(Sphingosine 1-phosphate receptor Edg-8 agonists)
Therapeutic Areas
Nervous System DiseasesEndocrinology and Metabolic DiseaseOther Diseases
Active Indication
Multiple System Atrophy
Inactive Indication-
Originator Organization
Ono Pharmaceutical Co., Ltd.Ono Pharmaceutical Co., Ltd.
Active Organization
Ono Pharmaceutical Co., Ltd.Ono Pharmaceutical Co., Ltd.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Related

3
Clinical Trials associated with ONO-2808
NCT05923866
/ Active, not recruitingPhase 2
A Phase 2, Double-blind, Placebo-controlled, Parallel-group Study Followed by an Open-label, Parallel Group Extension Part to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Potential Efficacy of Multiple Doses of ONO-2808 in Patients With Multiple System Atrophy
JPRN-jRCT2071200099
/ CompletedPhase 1IIT
ONO-2808-02:ONO-2808 Phase 1 study Single and multiple oral dose study in healthy adult male subjects, elderly male and female subjects
NCT04578028
/ CompletedPhase 1
A Randomised, Double Blind, Placebo Controlled, Single Centre, Three-Part Study to Assess the Safety, Tolerability and Pharmacokinetics of Single and Multiple Oral Doses of ONO-2808 in Healthy Subjects.
100 Clinical Results associated with ONO-2808
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100 Translational Medicine associated with ONO-2808
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100 Patents (Medical) associated with ONO-2808
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100 Deals associated with ONO-2808
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Neurodegenerative DiseasesPhase 3
United Kingdom
Ono Pharmaceutical Co., Ltd.Ono Pharmaceutical Co., Ltd.
19 Aug 2020
Multiple System AtrophyPhase 2
United States
Ono Pharmaceutical Co., Ltd.Ono Pharmaceutical Co., Ltd.
22 Sep 2023
Multiple System AtrophyPhase 2
Japan
Ono Pharmaceutical Co., Ltd.Ono Pharmaceutical Co., Ltd.
22 Sep 2023
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Clinical Result

Indication
Phase
Evaluation
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Phase
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Clinical Trial

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Approval

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Regulation

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