[68Ga]-DOTA-IBA

Nuclear protein in testis gene rearrangement-associated midline carcinoma (NUT carcinoma) is a rare and highly invasive tumor. Here, we are reporting the image findings of a 38-year-old woman with lung NUT carcinoma. To evaluate the bone metastases, she underwent 68Ga-labeled DOTA-ibandronic acid (68Ga-DOTA-IBA) PET/CT examination. Surprisingly, the patient’s lung primary focus and subcutaneous nodule on the left side of the lower back region showed increased uptake.

A 41-year-old woman with bone and liver metastasis of breast cancer was enrolled in our 68Ga-labeled DOTA-ibandronic acid (68Ga-DOTA-IBA) PET/CT tumor clinical trial. The examination revealed increased uptake of 68Ga-DOTA-IBA in the multiple bone metastases. Unexpectedly, 68Ga-DOTA-IBA uptake in meningioma and liver metastasis were also noted.