RP-HPLC Study of the Complexation of Acetamiprid, Imidacloprid and Carboxin Guest Molecules With Thiophosphorylated Calix [6] Arene in Dimethylformamide-Acetonitrile-Water Mobile Phase

Article

Author: Mishra, Vijay ; Sharma, Chandramauly R ; Agrawal, Yadvendra

AbstractReversed-phase high-performance liquid chromatography was used to study the host-guest complexation of thiophosphacalixarenes (TPC 1–3) with acetamiprid, imidacloprid and carboxin as guests. The Onyx Monolithic C 18 column (150 × 0.1 mm) and Phenomenex® were used with UV detection at 254 nm. The mobile phase consisted of dimethylformamide-acetonitrile-water. The association constant of the 1:1 guest-host complexes was determined from the relationship between the retention factor of the guest and concentration of the thiophosphacalix [6] arene host in the mobile phase. The stability constants are influenced by size, nature, position and quantity of substituents in the benzene ring of the calixarene skeleton. The detection limits for TPC 1, TPC 2 and TPC 3 are 0.95, 1.20 and 1.40 μg/mL, while the quantification limits are 2.85, 3.60 and 4.20 μg/mL for TPC 1, TPC 2 and TPC 3, respectively.

01 Dec 2024·International Journal of Biological Macromolecules

A new thermochromic crystal violet lactone/lactic acid/myristyl alcohol ternary mixture encapsulated with a poplar-based cellulose/lignin/SiO2 framework

Article

Author: Li, Cong ; Zou, Naike ; Zhang, Yujiao ; Song, Ling ; Han, Xiaoxu ; Zou, Weihua ; Sun, Delin

Two thermochromic poplar-based composites, TPC-1 and TPC-2, were fabricated using a crystal violet lactone (CVL)/lactic acid/myristyl alcohol ternary mixture. The mass ratios for TPC-1 and TPC-2 were 10: 3: 200 and 10: 80: 200, respectively. TPC-1 exhibits a common thermochromic property, reversibly changing color from blue to the natural hue of poplar within the temperature range of 28-48 °C. In contrast, TPC-2 demonstrates a novel thermochromic behavior, shifting from light blue to dark blue within the range of 30-52 °C. This work elucidates the correlations between the distinctive mass ratios in the ternary mixtures, the resulting CVL structures, and the consequent thermochromic properties. The blue TPC-1 exhibits an open lactone ring with a HO-C=O in its CVL structure. Similarly, the light-blue TPC-2 displays an open lactone ring with a HO-C=O. However, the dark-blue TPC-2 features an open lactone ring with a HO-C=O and a C-O-C. TPC-2 is a ternary mixture encapsulated with a poplar-based cellulose/lignin/SiO₂ framework. This integrated framework chemically interacts with the ternary mixture, enhancing phase-changing properties, heat-saving capabilities and mechanical properties of TPC-2. Consequently, TPC-2 is a promising candidate for applications as a temperature-responsive, thermal energy-storing, and structural material in building interiors.

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Indication	Highest Phase	Country/Location	Organization	Date
Eye Diseases	Discovery	United States	Warren Pharmaceuticals, Inc.	-
Heart Diseases	Discovery	United States	Warren Pharmaceuticals, Inc.	-
Kidney Diseases	Discovery	United States	Warren Pharmaceuticals, Inc.	-

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