Comparative evaluation of sealing potential of mineral trioxide aggregate, biodentine, and bio-C repair in furcation perforations: A glucose penetration study

Article

Author: Pal, Suditi ; Champa, C. ; Srirekha, A. ; Sultana, Hajira Anjum ; Shetty, Ashwija ; Sahithi, V.

AbstractIntroduction:Furcation perforation is a common dental issue that can result in substantial tooth loss if not repaired with a material that effectively seals the area. Mineral trioxide aggregate (MTA) and Biodentine have been previously studied for their sealing capabilities, but Bio-C Repair is a relatively new material that is yet to be evaluated. This study sought to compare and evaluate the sealing potential of MTA, Biodentine, and Bio-C Repair as furcation perforation repair materials using the glucose penetration method.Materials and Methods:Forty-five mandibular molars were sectioned 3 mm above the cementoenamel junction. Access openings were prepared, and intentional perforations were created in the pulpal floor using a round bur. The specimens were randomly divided into three groups of 15. Group 1 was repaired with MTA, Group 2 with Biodentine, and Group 3 with Bio-C Repair. The sealing potential was evaluated using a glucose penetration test. Data were analyzed using one-way analysis of variance with Tukey’s post hoc test.Results:The test results demonstrated that glucose penetration was significantly least in Group 3 (1.5313), followed by Group 1 (8.2208) and highest in Group 2 (8.5622) at P < 0.001.Conclusions:Within the study’s limitations, Bio-C Repair exhibited the best sealing ability for furcation perforations, followed by MTA and then Biodentine. Therefore, Bio-C Repair could be a suitable alternative to MTA and Biodentine for repairing furcal perforations.

01 Dec 2024·Australian Endodontic Journal

Reliability of sealer penetration measurement methods and assessment of dentine penetrability after endodontic retreatment: A correlation in vitro study

Article

Author: Almohazey, Dana ; Atmeh, Amre R. ; Aldawood, Sukainah A. ; Omar, Omar

AbstractThis study evaluated the reliability of sealer penetration measurement methods used with confocal laser scanning microscopy in correlation with the percentage of residual root filling and examined the effect of residual root‐filling material on dentine penetrability after retreatment. Extracted teeth were randomly divided into different groups according to the obturation sealer used (n = 6); BioRoot RCS; MTA Fillapex; Bio‐C and AH Plus. Root‐filling material was removed before the secondary chemo‐mechanical preparation and obturation using fluorescein labelled AH Plus. Multiple micro‐computed tomography scans were obtained followed by confocal laser scanning microscopy to measure the penetration of the labelled sealer into the dentinal tubules using four different methods. Measuring sealer penetration into radicular dentine using the penetration percentage method was found to be the most reliable. Dentine penetrability during retreatment did not seem to be affected by the type of residual root‐filling material.

01 Dec 2024·Journal of Pharmacy and Bioallied Sciences

Comparative Micro-CT Evaluation of Dentinal Tubule Penetration of BIO-C and AH Plus Jet Root Canal Sealer Using Three Intra-Canal Activation Techniques

Article

Author: Athira, P. M ; Sreelekshmi, V. ; Nair, Siddharth V. ; Jitha, J. ; Sreedhar, Sreeja ; Viswanadhan, Anitha ; Vivek, K.

ABSTRACTObjectives:This study aimed to compare the effectiveness of three intra-canal sealer activation techniques: ultrasonic, Lentulospiral activation, and GP cone-mediated ultrasonic activation on dentinal tubule penetration of a bioceramic (BIO-C) root canal sealer and AH Plus jet sealer with single cone obturation.Materials and Methods:Eighty single-rooted straight canal teeth were randomly divided into two main groups – BIO-C sealer and AH Plus jet sealer (n = 40). Each group was further divided into four subgroups, based on the three activation techniques: ultrasonics, Lentulospiral, gutta-percha cone-mediated ultrasonic, and a control. The canals were obturated using the single cone obturation technique. Dentinal penetration of sealers was measured using Micro-CT at the coronal, middle, and apical portions of root canals.Results:Greater sealer penetration was observed with ultrasonic and Lentulospiral agitation compared to GP-mediated ultrasonic agitation for both sealers.Conclusion:BIO-C yielded better results with ultrasonic and Lentulospiral agitation, while AH Plus performed better with ultrasonic agitation.

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Indication	Highest Phase	Country/Location	Organization	Date
Eye Infections	Preclinical	Sweden	in2cure AB	24 Feb 2022
Respiratory Distress Syndrome, Adult	Preclinical	Sweden	in2cure AB	24 Feb 2022
Wounds and Injuries	Preclinical	Sweden	in2cure AB	24 Feb 2022

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