Last update 22 May 2026

XM182-Exatecan

Overview

Basic Info

Drug Type
Peptide drug conjugates
Synonyms
XM182-01, XM182-MVCP-Exatecan
Target
IL-13Rα2 x Top I
Action
inhibitors
Mechanism
IL-13Rα2 inhibitors(Interleukin-13 receptor subunit alpha-2 inhibitors), TOP1 inhibitors(DNA topoisomerase I inhibitors)
Therapeutic Areas
NeoplasmsNervous System DiseasesOther Diseases
Active Indication
Diffuse Midline GliomaDiffuse Intrinsic Pontine Glioma
Inactive Indication-
Originator Organization
Excellamol, Inc.Excellamol, Inc.
Active Organization
Excellamol, Inc.Excellamol, Inc.
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
RegulationOrphan Drug (United States)

Structure/Sequence

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Related

100 Clinical Results associated with XM182-Exatecan
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100 Translational Medicine associated with XM182-Exatecan
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100 Patents (Medical) associated with XM182-Exatecan
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100 Deals associated with XM182-Exatecan
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Diffuse Midline GliomaPreclinical
South Korea
Excellamol, Inc.Excellamol, Inc.
01 Nov 2025
Diffuse Intrinsic Pontine GliomaPreclinical
South Korea
Excellamol, Inc.Excellamol, Inc.
17 Jun 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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