Last update 08 May 2025

LNF-2007

Overview

Basic Info

Drug Type
Bispecific T-cell Engager (BiTE)
Synonyms
Target
CD3 x CLDN18.2
Action
stimulants, modulators
Mechanism
CD3 stimulants(T cell surface glycoprotein CD3 stimulants), CLDN18.2 modulators(Claudin 18.2 modulators)
Therapeutic Areas
NeoplasmsDigestive System Disorders
Active Indication
Advanced Malignant Solid NeoplasmStomach Cancer
Inactive Indication-
Originator Organization
Lunan Pharmaceutical Group Co., Ltd.Lunan Pharmaceutical Group Co., Ltd.
Active Organization
Shandong New Time Pharmaceutical Co. Ltd.Shandong New Time Pharmaceutical Co. Ltd.Lunan Pharmaceutical Group Co., Ltd.Lunan Pharmaceutical Group Co., Ltd.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with LNF-2007
CTR20244873
/ RecruitingPhase 1
LNF2007单药治疗晚期实体瘤患者的安全性、耐受性、药代动力学/药效学特征及初步有效性的I期临床研究
[Translation] Phase I clinical study on the safety, tolerability, pharmacokinetic/pharmacodynamic characteristics and preliminary efficacy of LNF2007 monotherapy in patients with advanced solid tumors
NCT06752447
/ Not yet recruitingPhase 1
A Phase I Clinical Study of Safety, Tolerability, Pharmacokinetic/pharmacodynamic Characteristics and Initial Efficacy of LNF2007 Monotherapy in Patients with Advanced Solid Tumors
100 Clinical Results associated with LNF-2007
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100 Translational Medicine associated with LNF-2007
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100 Patents (Medical) associated with LNF-2007
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100 Deals associated with LNF-2007
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 1-
Shandong New Time Pharmaceutical Co. Ltd.Shandong New Time Pharmaceutical Co. Ltd.
20 Jan 2025
Stomach CancerPreclinical
China
Lunan Pharmaceutical Group Co., Ltd.Lunan Pharmaceutical Group Co., Ltd.
10 Apr 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Clinical Trial

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Approval

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Biosimilar

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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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