Last update 13 Dec 2025

Lead #2 (Mekanistic Therapeutics)

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms-
Target
EGFR x PI3Ks
Action
antagonists, modulators
Mechanism
EGFR antagonists(Epidermal growth factor receptor erbB1 antagonists), PI3K family modulators(Phosphatidylinositol 3-kinase family modulators)
Therapeutic Areas
NeoplasmsSkin and Musculoskeletal Diseases
Active Indication
Breast DiseasesSarcomaSquamous Cell Carcinoma of Head and Neck
Inactive Indication-
Originator Organization
Mekanistic Therapeutics LLCMekanistic Therapeutics LLC
Active Organization
Mekanistic Therapeutics LLCMekanistic Therapeutics LLC
Inactive Organization-
License Organization-
Drug Highest PhaseDiscovery
First Approval Date-
Regulation-

Related

100 Clinical Results associated with Lead #2 (Mekanistic Therapeutics)
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100 Translational Medicine associated with Lead #2 (Mekanistic Therapeutics)
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100 Patents (Medical) associated with Lead #2 (Mekanistic Therapeutics)
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100 Deals associated with Lead #2 (Mekanistic Therapeutics)
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Breast DiseasesDiscovery
United States
Mekanistic Therapeutics LLCMekanistic Therapeutics LLC
27 Jun 2024
SarcomaDiscovery
United States
Mekanistic Therapeutics LLCMekanistic Therapeutics LLC
27 Jun 2024
Squamous Cell Carcinoma of Head and NeckDiscovery
United States
Mekanistic Therapeutics LLCMekanistic Therapeutics LLC
27 Jun 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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