Delving into the Latest Updates on Retroviral SF71-gp91phox transduced CD34+ cells(Hospital of the Johann Wolfgang Goethe University) with Synapse

Overview

Basic Info

Drug Type

Gene therapy, Cell therapy

Synonyms-

Target-

Action-

Mechanism

Gene transference(Gene transference)

Therapeutic Areas

Immune System DiseasesCongenital DisordersHemic and Lymphatic Diseases+ [1]

Active Indication-

Inactive Indication

Granulomatous Disease, Chronic

Originator Organization

Hospital of the Johann Wolfgang Goethe University

Active Organization-

Inactive Organization

Johann Wolfgang Goethe-Universität Frankfurt am MainHospital of the Johann Wolfgang Goethe University

License Organization-

Drug Highest PhasePendingPhase 1/2

First Approval Date-

Regulation-

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The aim of the study is to evaluate the side effects and risks after infusion of retroviral gene corrected autologous CD34+ cells of the peripheral blood of chemotherapy conditioned (busulphan) children with chronic granulomatous disease (CGD). Also gene corrected and functional active granulocytes in the peripheral blood and the engraftment in the bone marrow of the patients will be monitored an documented.

Start Date01 Jun 2004

Sponsor / Collaborator

University of Zurich

[+1]

NCT00564759

/ Unknown statusPhase 1/2IIT

Phase I/II Gene Therapy Study for X-Linked Chronic Granulomatous Disease

The aim of the study is to evaluate the side effects and risks after infusion of retroviral gene corrected autologous CD34+ cells of the peripheral blood of chemotherapy conditioned (busulphan)patients with chronic granulomatous disease (CGD). Also gene corrected and functional active granulocytes in the peripheral blood and the engraftment in the bone marrow of the patients will be monitored an documented.

Start Date01 Jan 2004

Sponsor / Collaborator

Hospital of the Johann Wolfgang Goethe University

[+1]

100 Clinical Results associated with Retroviral SF71-gp91phox transduced CD34+ cells(Hospital of the Johann Wolfgang Goethe University)

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100 Translational Medicine associated with Retroviral SF71-gp91phox transduced CD34+ cells(Hospital of the Johann Wolfgang Goethe University)

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100 Patents (Medical) associated with Retroviral SF71-gp91phox transduced CD34+ cells(Hospital of the Johann Wolfgang Goethe University)

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100 Deals associated with Retroviral SF71-gp91phox transduced CD34+ cells(Hospital of the Johann Wolfgang Goethe University)

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